Effect of primaquine dose on the risk of recurrence in patients with uncomplicated Plasmodium vivax: a systematic review and individual patient data meta-analysis

RJ Commons, M Rajasekhar, P Edler… - The Lancet Infectious …, 2023 - thelancet.com
Background Primaquine is used to eliminate Plasmodium vivax hypnozoites, but its optimal
dosing regimen remains unclear. We undertook a systematic review and individual patient …

Diagnosis, treatment, and prevention of malaria in the US: a review

JP Daily, A Minuti, N Khan - Jama, 2022 - jamanetwork.com
Importance Malaria is caused by protozoa parasites of the genusPlasmodiumand is
diagnosed in approximately 2000 people in the US each year who have returned from …

IgM in human immunity to Plasmodium falciparum malaria

MJ Boyle, JA Chan, I Handayuni, L Reiling, G Feng… - Science …, 2019 - science.org
Most studies on human immunity to malaria have focused on the roles of immunoglobulin G
(IgG), whereas the roles of IgM remain undefined. Analyzing multiple human cohorts to …

Plasmodium knowlesi: the game changer for malaria eradication

WC Lee, FW Cheong, A Amir, MY Lai, JH Tan… - Malaria Journal, 2022 - Springer
Plasmodium knowlesi is a zoonotic malaria parasite that has gained increasing medical
interest over the past two decades. This zoonotic parasitic infection is prevalent in Southeast …

Platelets kill circulating parasites of all major Plasmodium species in human malaria

S Kho, BE Barber, E Johar, B Andries… - Blood, The Journal …, 2018 - ashpublications.org
Platelets are understood to assist host innate immune responses against infection, although
direct evidence of this function in any human disease, including malaria, is unknown. Here …

Pathogenicity and virulence of malaria: Sticky problems and tricky solutions

IS Walker, SJ Rogerson - Virulence, 2023 - Taylor & Francis
Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

Plasmodium knowlesi Malaria in Sabah, Malaysia, 2015–2017: Ongoing Increase in Incidence Despite Near-elimination of the Human-only Plasmodium Species

DJ Cooper, GS Rajahram, T William… - Clinical infectious …, 2020 - academic.oup.com
Background Malaysia aims to eliminate malaria by 2020. However, while cases of
Plasmodium falciparum and Plasmodium vivax have decreased substantially, the incidence …

Primaquine dose and the risk of haemolysis in patients with uncomplicated Plasmodium vivax malaria: a systematic review and individual patient data meta-analysis

M Rajasekhar, JA Simpson, B Ley, P Edler… - The Lancet Infectious …, 2023 - thelancet.com
Background Primaquine radical cure is used to treat dormant liver-stage parasites and
prevent relapsing Plasmodium vivax malaria but is limited by concerns of haemolysis. We …

Simian malaria: a narrative review on emergence, epidemiology and threat to global malaria elimination

KM Fornace, GZ Laporta, I Vythilingham… - The Lancet Infectious …, 2023 - thelancet.com
Simian malaria from wild non-human primate populations is increasingly recognised as a
public health threat and is now the main cause of human malaria in Malaysia and some …

Prevalence of severe Plasmodium knowlesi infection and risk factors related to severe complications compared with non-severe P. knowlesi and severe P. falciparum …

M Kotepui, KU Kotepui, GD Milanez… - Infectious Diseases of …, 2020 - Springer
Background Plasmodium knowlesi is a potential cause of severe and fatal malaria, but
comprehensive studies of its pooled prevalence and risk factors are lacking. This study …