The role of m6A RNA methylation in cancer metabolism

Y An, H Duan - Molecular cancer, 2022 - Springer
Metabolic reprogramming is one of the main characteristics of malignant tumors, which is
due to the flexible changes of cell metabolism that can meet the needs of cell growth and …

Protein arginine methylation: from enigmatic functions to therapeutic targeting

Q Wu, M Schapira, CH Arrowsmith… - Nature reviews Drug …, 2021 - nature.com
Protein arginine methyltransferases (PRMTs) are emerging as attractive therapeutic targets.
PRMTs regulate transcription, splicing, RNA biology, the DNA damage response and cell …

Non-coding RNA in cancer

H Yan, P Bu - Essays in biochemistry, 2021 - portlandpress.com
Majority of the human genome is transcribed to RNAs that do not encode proteins. These
non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of …

The physics of fast radio bursts

B Zhang - Reviews of Modern Physics, 2023 - APS
Fast radio bursts (FRBs), millisecond-duration bursts prevailing in the radio sky, are the
latest large puzzle in the Universe and have been a subject of intense observational and …

The regulation, functions and clinical relevance of arginine methylation

E Guccione, S Richard - Nature reviews Molecular cell biology, 2019 - nature.com
Methylation of arginine residues by protein arginine methyltransferases (PRMTs) is involved
in the regulation of fundamental cellular processes, including transcription, RNA processing …

LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer

Y Wang, JH Lu, QN Wu, Y Jin, DS Wang, YX Chen… - Molecular cancer, 2019 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) play nonnegligible roles in the
epigenetic regulation of cancer cells. This study aimed to identify a specific lncRNA that …

LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc

J Tang, T Yan, Y Bao, C Shen, C Yu, X Zhu… - Nature …, 2019 - nature.com
Long non-coding RNAs (lncRNAs) contribute to colorectal cancer (CRC). However, the role
of lncRNAs in CRC metabolism, especially glucose metabolism remains largely unknown. In …

[HTML][HTML] PRMT5 function and targeting in cancer

H Kim, AR Ze'ev - Cell stress, 2020 - ncbi.nlm.nih.gov
Protein methyl transferases play critical roles in numerous regulatory pathways that underlie
cancer development, progression and therapy-response. Here we discuss the function of …

RETRACTED ARTICLE: The LINC00623/NAT10 signaling axis promotes pancreatic cancer progression by remodeling ac4C modification of mRNA

Z Feng, K Li, K Qin, J Liang, M Shi, Y Ma… - Journal of hematology & …, 2022 - Springer
Background Although a substantial increase in the survival of patients with other cancers
has been observed in recent decades, pancreatic ductal adenocarcinoma (PDAC) remains …

LINC00460/DHX9/IGF2BP2 complex promotes colorectal cancer proliferation and metastasis by mediating HMGA1 mRNA stability depending on m6A modification

P Hou, S Meng, M Li, T Lin, S Chu, Z Li, J Zheng… - Journal of Experimental …, 2021 - Springer
Background Increasing studies have shown that long noncoding RNAs (lncRNAs) are
pivotal regulators participating in carcinogenic progression and tumor metastasis in …