[HTML][HTML] Mesenchymal stem cell-derived exosome microRNA as therapy for cardiac ischemic injury

MI Nasser, M Masood, S Adlat, D Gang, S Zhu… - Biomedicine & …, 2021 - Elsevier
Cardiovascular diseases (CVD) are a significant cause of human health harm. In the past,
stem cell therapy was reported to have functional defects, such as immune rejection …

miRPathDB 2.0: a novel release of the miRNA Pathway Dictionary Database

T Kehl, F Kern, C Backes, T Fehlmann… - Nucleic acids …, 2020 - academic.oup.com
Since the initial release of miRPathDB, tremendous progress has been made in the field of
microRNA (miRNA) research. New miRNA reference databases have emerged, a vast …

Factors defining human adipose stem/stromal cell immunomodulation in vitro

M Mahmoud, M Abdel-Rasheed, ER Galal… - Stem Cell Reviews and …, 2024 - Springer
Human adipose tissue-derived stem/stromal cells (hASCs) are adult multipotent
mesenchymal stem/stromal cells with immunomodulatory capacities. Here, we present up-to …

[HTML][HTML] Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation

P Chen, S Tang, H Gao, H Zhang, C Chen… - International Journal of …, 2022 - Elsevier
The main strategy of tissue repair and regeneration focuses on the application of
mesenchymal stem cells and cell-based nanoparticles, but there are still multiple challenges …

Cartilage protective and immunomodulatory features of osteoarthritis synovial fluid-treated adipose-derived mesenchymal stem cells secreted factors and extracellular …

E Ragni, A Colombini, M Viganò, F Libonati… - Cells, 2021 - mdpi.com
Intra-articular administration of adipose-derived mesenchymal stem cells (ASCs), either in
vitro expanded or within adipose tissue-based products obtained at point-of-care, has …

[HTML][HTML] Control of articular degeneration by extracellular vesicles from stem/stromal cells as a potential strategy for the treatment of osteoarthritis

MJ Alcaraz - Biochemical Pharmacology, 2024 - Elsevier
Osteoarthritis (OA) is a degenerative joint condition that contributes to years lived with
disability. Current therapeutic approaches are limited as there are no disease-modifying …

Is extracellular vesicle-based therapy the next answer for cartilage regeneration?

E Velot, H Madry, JK Venkatesan, A Bianchi… - … in Bioengineering and …, 2021 - frontiersin.org
“Extracellular vesicles”(EVs) is a term gathering biological particles released from cells that
act as messengers for cell-to-cell communication. Like cells, EVs have a membrane with a …

[HTML][HTML] MSC-EV therapy for bone/cartilage diseases

J Kodama, KJ Wilkinson, S Otsuru - Bone reports, 2022 - Elsevier
Mesenchymal stromal cells (MSCs) have been utilized in cell therapy for various diseases.
Recent studies have demonstrated that extracellular vesicles (EVs) released by MSCs play …

Mesenchymal stem cell-derived extracellular vesicles: a potential therapeutic strategy for acute kidney injury

JK Li, C Yang, Y Su, JC Luo, MH Luo… - Frontiers in …, 2021 - frontiersin.org
Acute kidney injury (AKI) is a common and potential life-threatening disease in patients
admitted to hospital, affecting 10%–15% of all hospitalizations and around 50% of patients …

Housekeeping Gene Stability in Adipose Mesenchymal Stromal Cells Cultivated in Serum/Xeno-Free Media for Osteoarthritis

E Ragni, S Piccolo, P De Luca, M Taiana, G Grieco… - Cells, 2024 - mdpi.com
Among the available therapeutics for the conservative treatment of osteoarthritis (OA),
mesenchymal stromal cells (MSCs)-based products appear to be the most promising …