The physics of heart rhythm disorders
WJ Rappel - Physics reports, 2022 - Elsevier
The global burden caused by cardiovascular disease is substantial, with heart disease
representing the most common cause of death around the world. There remains a need to …
representing the most common cause of death around the world. There remains a need to …
Computational modeling of the human atrial anatomy and electrophysiology
This review article gives a comprehensive survey of the progress made in computational
modeling of the human atria during the last 10 years. Modeling the anatomy has emerged …
modeling of the human atria during the last 10 years. Modeling the anatomy has emerged …
Patient-derived models link re-entrant driver localization in atrial fibrillation to fibrosis spatial pattern
Aims The mechanisms underlying persistent atrial fibrillation (AF) in patients with atrial
fibrosis are poorly understood. The goal of this study was to use patient-derived atrial …
fibrosis are poorly understood. The goal of this study was to use patient-derived atrial …
Modeling cardiac muscle fibers in ventricular and atrial electrophysiology simulations
Since myocardial fibers drive the electric signal propagation throughout the myocardium,
accurately modeling their arrangement is essential for simulating heart electrophysiology …
accurately modeling their arrangement is essential for simulating heart electrophysiology …
Preprocedure application of machine learning and mechanistic simulations predicts likelihood of paroxysmal atrial fibrillation recurrence following pulmonary vein …
Background: Pulmonary vein isolation (PVI) is an effective treatment strategy for patients
with atrial fibrillation (AF), but many experience AF recurrence and require repeat ablation …
with atrial fibrillation (AF), but many experience AF recurrence and require repeat ablation …
[HTML][HTML] Universal atrial coordinates applied to visualisation, registration and construction of patient specific meshes
Integrating spatial information about atrial physiology and anatomy in a single patient from
multimodal datasets, as well as generalizing these data across patients, requires a common …
multimodal datasets, as well as generalizing these data across patients, requires a common …
Constructing a human atrial fibre atlas
Atrial anisotropy affects electrical propagation patterns, anchor locations of atrial reentrant
drivers, and atrial mechanics. However, patient-specific atrial fibre fields and anisotropy …
drivers, and atrial mechanics. However, patient-specific atrial fibre fields and anisotropy …
lifex-fiber: an open tool for myofibers generation in cardiac computational models
Background Modeling the whole cardiac function involves the solution of several complex
multi-physics and multi-scale models that are highly computationally demanding, which call …
multi-physics and multi-scale models that are highly computationally demanding, which call …
Slow conduction in the border zones of patchy fibrosis stabilizes the drivers for atrial fibrillation: insights from multi-scale human atrial modeling
Introduction: The genesis of atrial fibrillation (AF) and success of AF ablation therapy have
been strongly linked with atrial fibrosis. Increasing evidence suggests that patient-specific …
been strongly linked with atrial fibrosis. Increasing evidence suggests that patient-specific …
Methodology for patient-specific modeling of atrial fibrosis as a substrate for atrial fibrillation
KS McDowell, F Vadakkumpadan, R Blake… - Journal of …, 2012 - Elsevier
Personalized computational cardiac models are emerging as an important tool for studying
cardiac arrhythmia mechanisms, and have the potential to become powerful instruments for …
cardiac arrhythmia mechanisms, and have the potential to become powerful instruments for …