[HTML][HTML] Dissection of Targeting Molecular Mechanisms of Celastrol-induced Nephrotoxicity via A Combined Deconvolution Strategy of Chemoproteomics and …

X Liu, Q Zhang, P Wang, X Peng, Y An… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Celastrol (Cel), derived from the traditional herb Tripterygium wilfordii Hook. f., has anti-
inflammatory, anti-tumor, and immunoregulatory activities. Renal dysfunction, including …

Disulfide bond-based oxidation-responsive triptolide-loaded nanodrug for inflammation-targeted treatment of collagen-induced arthritis

H Zeng, M Li, Z Wang, T Wang, Z Zhang, X Wu - Applied Materials Today, 2024 - Elsevier
M1 macrophages play a crucial role in the development of rheumatoid arthritis (RA), which
can produce various inflammation cytokines, and reactive oxygen species (ROS). Disulfide …

A biomimetic, triggered‐release micelle formulation of methotrexate and celastrol controls collagen‐induced arthritis in mice

H Ren, Z Wu, J Li, N Zhang, CY Nah, J Li, J Zhang… - …, 2024 - Wiley Online Library
Rheumatoid arthritis (RA) is a systemic autoimmune disease that leads to the destruction of
articular cartilage and bone. RA is characterized by immune cell infiltration and abnormal …

雷公藤多苷片合理用药评价标准的建立与应用.

王欠欠 - Practical Pharmacy & Clinical Remedies, 2024 - search.ebscohost.com
目的建立雷公藤多苷片(Tripterygium glycoside tablets, TGT) 合理用药评价标准, 促进TGT
的临床合理应用. 方法依据循证医学证据建立TGT 合理用药评价标准, 应用该标准对安徽中医药 …