New horizons for newborn brain protection: enhancing endogenous neuroprotection

KJ Hassell, M Ezzati, D Alonso-Alconada… - Archives of Disease in …, 2015 - fn.bmj.com
Intrapartum-related events are the third leading cause of childhood mortality worldwide and
result in one million neurodisabled survivors each year. Infants exposed to a perinatal insult …

Ischemic postconditioning as a novel avenue to protect against brain injury after stroke

H Zhao - Journal of Cerebral Blood Flow & Metabolism, 2009 - journals.sagepub.com
Ischemic postconditioning initially referred to a stuttering reperfusion performed immediately
after reperfusion, for preventing ischemia/reperfusion injury in both myocardial and cerebral …

RECAST (remote ischemic conditioning after stroke trial) a pilot randomized placebo controlled phase II trial in acute ischemic stroke

TJ England, A Hedstrom, S O'Sullivan, R Donnelly… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Repeated episodes of limb ischemia and reperfusion (remote
ischemic conditioning [RIC]) may improve outcome after acute stroke. Methods—We …

Limb remote ischemic postconditioning protects against focal ischemia in rats

C Ren, Z Yan, D Wei, X Gao, X Chen, H Zhao - Brain research, 2009 - Elsevier
Remote ischemic postconditioning (RIP) refers to an ischemia conducted in a distant organ
that protects against a prior ischemia in another organ. We tested whether RIP protects …

Remote ischemic per-conditioning: a novel therapy for acute stroke?

CD Hahn, C Manlhiot, MR Schmidt, TT Nielsen… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—Remote ischemic preconditioning is a phenomenon by which a
short period of sublethal ischemia to an organ protects against subsequent ischemia in …

From rapid to delayed and remote postconditioning: the evolving concept of ischemic postconditioning in brain ischemia

H Zhao, C Ren, X Chen, J Shen - Current drug targets, 2012 - ingentaconnect.com
Ischemic postconditioning is a concept originally defined to contrast with that of ischemic
preconditioning. While both preconditioning and postconditioning confer a neuroprotective …

[HTML][HTML] Remote ischemic conditioning: a promising therapeutic intervention for multi-organ protection

D Zhou, J Ding, J Ya, L Pan, Y Wang, X Ji… - Aging (Albany NY …, 2018 - ncbi.nlm.nih.gov
Despite decades of formidable exploration, multi-organ ischemia-reperfusion injury (IRI)
encountered, particularly amongst elderly patients with clinical scenarios, such as age …

Protective Effect of Delayed Remote Limb Ischemic Postconditioning: Role of Mitochondrial KATP Channels in a Rat Model of Focal Cerebral Ischemic Reperfusion …

J Sun, T Li, Q Luan, J Deng, Y Li, Z Li… - Journal of Cerebral …, 2012 - journals.sagepub.com
Delayed remote ischemic postconditioning (DRIPost) has been shown to protect the rat
brain from ischemic injury. However, extremely short therapeutic time windows hinder its …

Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse

C Leconte, E Tixier, T Freret, J Toutain, R Saulnier… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—Inspired from preconditioning studies, ischemic
postconditioning, consisting of the application of intermittent interruptions of blood flow …

Clinical application of preconditioning and postconditioning to achieve neuroprotection

C Dezfulian, M Garrett, NR Gonzalez - Translational stroke research, 2013 - Springer
Ischemic conditioning is a form of endogenous protection induced by transient, subcritical
ischemia in a tissue. Organs with high sensitivity to ischemia, such as the heart, the brain …