Cardiovascular disease in diabetes, beyond glucose

RH Eckel, KE Bornfeldt, IJ Goldberg - Cell metabolism, 2021 - cell.com
Despite the decades-old knowledge that diabetes mellitus is a major risk factor for
cardiovascular disease, the reasons for this association are only partially understood. While …

Mediterranean diet nutrients to turn the tide against insulin resistance and related diseases

M Mirabelli, E Chiefari, B Arcidiacono, DM Corigliano… - Nutrients, 2020 - mdpi.com
Insulin resistance (IR), defined as an attenuated biological response to circulating insulin, is
a fundamental defect in obesity and type 2 diabetes (T2D), and is also linked to a wide …

Triglyceride glucose-body mass index and the risk of diabetes: a general population-based cohort study

X Wang, J Liu, Z Cheng, Y Zhong, X Chen… - Lipids in health and …, 2021 - Springer
Background Triglyceride glucose-body mass index (TyG-BMI) has been proven to be a
reliable substitute for insulin resistance. However, whether a causal association exists …

The lipid profiles in different characteristics of women with PCOS and the interaction between dyslipidemia and metabolic disorder states: a retrospective study in …

F Guo, Z Gong, T Fernando, L Zhang, X Zhu… - Frontiers in …, 2022 - frontiersin.org
Purpose To exhibit the lipid profiles in PCOS women with different characteristics and to
access correlations between alternation of key lipid parameters and characteristics of PCOS …

The roles of dietary lipids and lipidomics in gut-brain axis in type 2 diabetes mellitus

D Ağagündüz, MA Icer, O Yesildemir, T Koçak… - Journal of translational …, 2023 - Springer
Type 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases
(NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β …

Mechanisms linking hypertriglyceridemia to acute pancreatitis

L Kiss, G Fűr, S Pisipati, P Rajalingamgari… - Acta …, 2023 - Wiley Online Library
Hypertriglyceridemia (HTG) is a metabolic disorder, defined when serum or plasma
triglyceride concentration (seTG) is> 1.7 mM. HTG can be categorized as mild to very severe …

HOMA-IR as a predictor of health outcomes in patients with metabolic risk factors: a systematic review and meta-analysis

JG González-González, JR Violante-Cumpa… - High Blood Pressure & …, 2022 - Springer
Introduction There exists clinical interest in the following question: Is there an association
between HOMA-IR and the risk of developing metabolic diseases? Aims Assessing the …

The association of surrogates of insulin resistance with hyperuricemia among middle-aged and older individuals: a population-based nationwide cohort study

Y Han, Z Zhou, Y Zhang, G Zhao, B Xu - Nutrients, 2023 - mdpi.com
The triglyceride–glucose (TyG) index, triglyceride-to-high-density-lipoprotein-cholesterol
(TG/HDL-C) ratio, metabolic score for insulin resistance (METS-IR) and TyG with body mass …

The association between physical activity and insulin level under different levels of lipid indices and serum uric acid

Y Lin, R Fan, Z Hao, J Li, X Yang, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Objectives Insulin resistance (IR) has been shown to play important role in the pathogenesis
of type 2 diabetes mellitus (T2DM). There is an intricate interplay between IR, dyslipidemia …

High-throughput functional dissection of noncoding SNPs with biased allelic enhancer activity for insulin resistance-relevant phenotypes

YY Duan, XF Chen, RJ Zhu, YY Jia, XT Huang… - The American Journal of …, 2023 - cell.com
Most of the single-nucleotide polymorphisms (SNPs) associated with insulin resistance (IR)-
relevant phenotypes by genome-wide association studies (GWASs) are located in …