Biomolecular condensates, membrane-less entities arising from liquid–liquid phase
separation, hold dichotomous roles in health and disease. Alongside their physiological …

This review highlights recent efforts on applying electron microscopy (EM) to soft (including
biological) nanomaterials. We will show how developments of both the hardware and …

Bone metastasis remains a challenge in cancer treatment. Here we show enzymatic
responsive rigid-rod aromatics acting as the substrates of “undruggable” phosphatases to …

While early genetic and low-resolution structural observations suggested that extracellular
conductive filaments on metal-reducing organisms such as Geobacter were composed of …

A fundamental endeavour in macromolecular science is the control of molecular-level
complexity, including molecular weight distribution, end groups and architecture. Since the …

While biofilms formed by bacteria have received great attention due to their importance in
pathogenesis, much less research has been focused on the biofilms formed by archaea. It …

The recent revolution in cryo-electron microscopy (cryo-EM) has made it possible to
determine macromolecular structures directly from cell extracts. However, identifying the …

The understanding of how short peptide assemblies transit from disorder to order remains
limited due to the lack of atomistic structures. Here, we report the cryo-EM structure of the …

The ability to engineer synthetic polymers with the same structural precision as
biomacromolecules is crucial to enable the de novo design of robust nanomaterials with …

Supramolecular assemblies made by the self‐assembly of peptides are finding an
increasing number of applications in various fields. While the early exploration of peptide …