Role of cholinergic signaling in Alzheimer's disease

ZR Chen, JB Huang, SL Yang, FF Hong - Molecules, 2022 - mdpi.com
Acetylcholine, a neurotransmitter secreted by cholinergic neurons, is involved in signal
transduction related to memory and learning ability. Alzheimer's disease (AD), a progressive …

Therapeutic potential of quercetin: new insights and perspectives for human health

B Salehi, L Machin, L Monzote, J Sharifi-Rad… - ACS …, 2020 - ACS Publications
Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising
bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti …

Antioxidant and oxidative stress: a mutual interplay in age-related diseases

BL Tan, ME Norhaizan, WPP Liew… - Frontiers in …, 2018 - frontiersin.org
Aging is the progressive loss of organ and tissue function over time. Growing older is
positively linked to cognitive and biological degeneration such as physical frailty …

Valorisation of citrus processing waste: A review

DA Zema, PS Calabrò, A Folino, V Tamburino… - Waste management, 2018 - Elsevier
This study analyses the quantitative and qualitative characteristics of citrus peel waste and
discusses the systems for its valorisation. Citrus peel waste (CPW) is the main residue of the …

Molecular mechanisms underlying protective role of quercetin in attenuating Alzheimer's disease

E Zaplatic, M Bule, SZA Shah, MS Uddin, K Niaz - Life sciences, 2019 - Elsevier
Quercetin belongs to the flavonoids family, which is present in most of the plants including
fruits, vegetables, green tea and even in red wine having antioxidant activities. It is available …

Innovative technologies for extraction and microencapsulation of bioactives from plant-based food waste and their applications in functional food development

M Pattnaik, P Pandey, GJO Martin, HN Mishra… - Foods, 2021 - mdpi.com
The by-products generated from the processing of fruits and vegetables (F&V) largely are
underutilized and discarded as organic waste. These organic wastes that include seeds …

Reactive oxygen species as a link between antioxidant pathways and autophagy

D Li, Z Ding, K Du, X Ye… - Oxidative Medicine and …, 2021 - Wiley Online Library
Reactive oxygen species (ROS) are highly reactive molecules that can oxidize proteins,
lipids, and DNA. Under physiological conditions, ROS are mainly generated in the …

Frailty, cognitive decline, neurodegenerative diseases and nutrition interventions

ME Gómez-Gómez, SC Zapico - International Journal of Molecular …, 2019 - mdpi.com
Currently the human population is aging faster. This leads to higher dependency rates and
the transformation of health and social care to adapt to this aged population. Among the …

Antioxidant compounds from edible mushrooms as potential candidates for treating age-related neurodegenerative diseases

GM Liuzzi, T Petraglia, T Latronico, A Crescenzi… - Nutrients, 2023 - mdpi.com
The last century has seen an increase in our life expectancy. As a result, various age-related
diseases, such as neurodegenerative diseases (NDs), have emerged, representing new …

Nobiletin and derivatives: functional compounds from citrus fruit peel for colon cancer chemoprevention

JXH Goh, LTH Tan, JK Goh, KG Chan, P Pusparajah… - Cancers, 2019 - mdpi.com
The search for effective methods of cancer treatment and prevention has been a continuous
effort since the disease was discovered. Recently, there has been increasing interest in …