Molecular mechanisms of oxidative stress in asthma

C Michaeloudes, H Abubakar-Waziri, R Lakhdar… - Molecular aspects of …, 2022 - Elsevier
The lungs are exposed to reactive oxygen species oxygen (ROS) produced as a result of
inhalation of oxygen, as well as smoke and other air pollutants. Cell metabolism and the …

Overview of the mechanisms of oxidative stress: impact in inflammation of the airway diseases

GD Albano, RP Gagliardo, AM Montalbano, M Profita - Antioxidants, 2022 - mdpi.com
Inflammation of the human lung is mediated in response to different stimuli (eg, physical,
radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental …

Thioredoxins, glutaredoxins, and peroxiredoxins—molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling

EM Hanschmann, JR Godoy, C Berndt… - Antioxidants & redox …, 2013 - liebertpub.com
Abstract Thioredoxins (Trxs), glutaredoxins (Grxs), and peroxiredoxins (Prxs) have been
characterized as electron donors, guards of the intracellular redox state, and “antioxidants” …

Nitric oxide production and signaling in inflammation

R Korhonen, A Lahti, H Kankaanranta… - Current Drug Targets …, 2005 - ingentaconnect.com
Nitric oxide (NO) is recognized as a mediator and regulator of inflammatory responses. It
possesses cytotoxic properties that are aimed against pathogenic microbes, but it can also …

[图书][B] Oxidation and antioxidants in organic chemistry and biology

ET Denisov, IB Afanas' ev - 2005 - taylorfrancis.com
Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …

Nitric oxide in health and disease of the respiratory system

FLM Ricciardolo, PJ Sterk, B Gaston… - Physiological …, 2004 - journals.physiology.org
During the past decade a plethora of studies have unravelled the multiple roles of nitric
oxide (NO) in airway physiology and pathophysiology. In the respiratory tract, NO is …

Particulate air pollutants and asthma: a paradigm for the role of oxidative stress in PM-induced adverse health effects

N Li, M Hao, RF Phalen, WC Hinds, AE Nel - Clinical immunology, 2003 - Elsevier
Asthma is a chronic inflammatory disease, which involves a variety of different mediators,
including reactive oxygen species. There is growing awareness that particulate pollutants …

FeNO in asthma

L Loewenthal, A Menzies-Gow - Seminars in respiratory and …, 2022 - thieme-connect.com
Asthma is a common disease affecting 350 million people worldwide, which is characterized
by airways inflammation and hyperreactivity. Historically diagnosis and treatment have been …

A review of breath analysis for diagnosis of human health

KH Kim, SA Jahan, E Kabir - TrAC Trends in Analytical Chemistry, 2012 - Elsevier
In this review, we describe technical developments in breath analysis and its applications in
clinical diagnosis, monitoring disease state, and assessing environmental exposure. Breath …

Inducible nitric oxide synthase and inflammatory diseases

R Zamora, Y Vodovotz, TR Billiar - Molecular medicine, 2000 - Springer
Nitric oxide (NO) is a colorless gas at room temperature and one of the simplest molecules
known, yet it has been implicated in a wide variety of regulatory mechanisms ranging from …