Stimuli‐responsive nanocomposite hydrogels for biomedical applications
P Lavrador, MR Esteves, VM Gaspar… - Advanced Functional …, 2021 - Wiley Online Library
The complex tissue‐specific physiology that is orchestrated from the nano‐to the
macroscale, in conjugation with the dynamic biophysical/biochemical stimuli underlying …
macroscale, in conjugation with the dynamic biophysical/biochemical stimuli underlying …
Polymeric delivery of therapeutic nucleic acids
R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Designing hydrogels for controlled drug delivery
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery
and have found clinical use. Hydrogels can provide spatial and temporal control over the …
and have found clinical use. Hydrogels can provide spatial and temporal control over the …
Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
CRISPR/Cas9-based genome editing for disease modeling and therapy: challenges and opportunities for nonviral delivery
Genome editing offers promising solutions to genetic disorders by editing DNA sequences
or modulating gene expression. The clustered regularly interspaced short palindromic …
or modulating gene expression. The clustered regularly interspaced short palindromic …
Emerging role of hydrogels in drug delivery systems, tissue engineering and wound management
The popularity of hydrogels as biomaterials lies in their tunable physical properties, ability to
encapsulate small molecules and macromolecular drugs, water holding capacity, flexibility …
encapsulate small molecules and macromolecular drugs, water holding capacity, flexibility …
[HTML][HTML] Various methods of gold nanoparticles (GNPs) conjugation to antibodies
MH Jazayeri, H Amani, AA Pourfatollah… - Sensing and bio …, 2016 - Elsevier
The unique properties of gold nanoparticles, their rich surface chemistry, and low toxicity as
well as easy methods of synthesis have promoted conjugation of the particles with …
well as easy methods of synthesis have promoted conjugation of the particles with …
Current state of knowledge on intelligent-response biological and other macromolecular hydrogels in biomedical engineering: A review
M Su, L Ruan, X Dong, S Tian, W Lang, M Wu… - International Journal of …, 2023 - Elsevier
Because intelligent hydrogels have good biocompatibility, a rapid response, and good
degradability as well as a stimulus response mode that is rich, hydrophilic, and similar to the …
degradability as well as a stimulus response mode that is rich, hydrophilic, and similar to the …
Polymeric Nanoparticles for Drug Delivery
MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …
necessitated the creation of more sophisticated drug delivery systems. Polymeric …
RNA-polymer hybrids via direct and site-selective acylation with the ATRP initiator and photoinduced polymerization
Combining synthetic polymers with RNA paves the way for creating RNA-based materials
with non-canonical functions. We have developed an acylation reagent that allows for direct …
with non-canonical functions. We have developed an acylation reagent that allows for direct …