An overview into polyethylene terephthalate (PET) hydrolases and efforts in tailoring enzymes for improved plastic degradation
NFS Khairul Anuar, F Huyop, G Ur-Rehman… - International journal of …, 2022 - mdpi.com
Plastic or microplastic pollution is a global threat affecting ecosystems, with the current
generation reaching as much as 400 metric tons per/year. Soil ecosystems comprising …
generation reaching as much as 400 metric tons per/year. Soil ecosystems comprising …
Sequence characterization and molecular modeling of clinically relevant variants of the SARS-CoV-2 main protease
The SARS-CoV-2 main protease (M pro) is essential to viral replication and cleaves highly
specific substrate sequences, making it an obvious target for inhibitor design. However, as …
specific substrate sequences, making it an obvious target for inhibitor design. However, as …
Comparative exploratory analysis of intrinsically disordered protein dynamics using machine learning and network analytic methods
Simulations of intrinsically disordered proteins (IDPs) pose numerous challenges to
comparative analysis, prominently including highly dynamic conformational states and a …
comparative analysis, prominently including highly dynamic conformational states and a …
Mutation effects on structure and dynamics: adaptive evolution of the SARS-CoV-2 main protease
The main protease of SARS-CoV-2 (Mpro) plays a critical role in viral replication; although it
is relatively conserved, Mpro has nevertheless evolved over the course of the COVID-19 …
is relatively conserved, Mpro has nevertheless evolved over the course of the COVID-19 …
A cold‐active esterase enhances mesophilic properties through Mn2+ binding
A key aspect of adaptation to cold environments is the production of cold‐active enzymes by
psychrophilic organisms. These enzymes not only have high activity at low temperatures, but …
psychrophilic organisms. These enzymes not only have high activity at low temperatures, but …
Neural upscaling from residue-level protein structure networks to atomistic structures
Coarse-graining is a powerful tool for extending the reach of dynamic models of proteins
and other biological macromolecules. Topological coarse-graining, in which biomolecules …
and other biological macromolecules. Topological coarse-graining, in which biomolecules …
The Droserasin 1 PSI: A Membrane-Interacting Antimicrobial Peptide from the Carnivorous Plant Drosera capensis
MA Sprague-Piercy, JC Bierma, MG Crosby… - Biomolecules, 2020 - mdpi.com
The Droserasins, aspartic proteases from the carnivorous plant Drosera capensis, contain a
100-residue plant-specific insert (PSI) that is post-translationally cleaved and independently …
100-residue plant-specific insert (PSI) that is post-translationally cleaved and independently …
Exploitation of active site flexibility-low temperature activity relation for engineering broad range temperature active enzymes
S Dasetty, JWP Zajac, S Sarupria - Molecular Systems Design & …, 2023 - pubs.rsc.org
Differences in the structural and thermodynamic properties of enzymes adapted to different
temperatures indicate that broad range temperature active enzymes can be designed by …
temperatures indicate that broad range temperature active enzymes can be designed by …
[图书][B] Client-Chaperone Selectivity, Solubility, and Hydrogel Characteristics of Human Crystallins and the Properties of D1-PSI
MA Sprague-Piercy - 2021 - search.proquest.com
For the eye lens to function correctly, it must be transparent and refract visible light strongly
enough to form an image on the retina. The bulk of this unique tissue is made of layers of …
enough to form an image on the retina. The bulk of this unique tissue is made of layers of …