Functional lung imaging in radiation therapy for lung cancer: A systematic review and meta-analysis

NW Bucknell, N Hardcastle, M Bressel… - Radiotherapy and …, 2018 - Elsevier
Rationale Advanced imaging techniques allow functional information to be derived and
integrated into treatment planning. Methods A systematic review was conducted with the …

Functional image-guided radiotherapy planning for normal lung avoidance

RH Ireland, BA Tahir, JM Wild, CE Lee, MQ Hatton - Clinical Oncology, 2016 - Elsevier
For patients with lung cancer undergoing curative intent radiotherapy, functional lung
imaging can be incorporated into treatment planning to modify the dose distribution within …

Use of 4-dimensional computed tomography-based ventilation imaging to correlate lung dose and function with clinical outcomes

Y Vinogradskiy, R Castillo, E Castillo, SL Tucker… - International Journal of …, 2013 - Elsevier
PURPOSE: Four-dimensional computed tomography (4DCT)-based ventilation is an
emerging imaging modality that can be used in the thoracic treatment planning process. The …

Validating and improving CT ventilation imaging by correlating with ventilation 4D‐PET/CT using 68Ga‐labeled nanoparticles

J Kipritidis, S Siva, MS Hofman, J Callahan… - Medical …, 2014 - Wiley Online Library
Purpose: CT ventilation imaging is a novel functional lung imaging modality based on
deformable image registration. The authors present the first validation study of CT ventilation …

Evaluating the toxicity reduction with computed tomographic ventilation functional avoidance radiation therapy

AM Faught, Y Miyasaka, N Kadoya, R Castillo… - International Journal of …, 2017 - Elsevier
Purpose Computed tomographic (CT) ventilation imaging is a new modality that uses 4-
dimensional (4D) CT information to calculate lung ventilation. Although retrospective studies …

[HTML][HTML] Micro-CT-derived ventilation biomarkers for the longitudinal assessment of pathology and response to therapy in a mouse model of lung fibrosis

F Pennati, L Leo, E Ferrini, N Sverzellati, D Bernardi… - Scientific Reports, 2023 - nature.com
Experimental in-vivo animal models are key tools to investigate the pathogenesis of lung
disease and to discover new therapeutics. Histopathological and biochemical investigations …

Hyperpolarized 3He magnetic resonance imaging: comparison with four-dimensional x-ray computed tomography imaging in lung cancer

L Mathew, A Wheatley, R Castillo, E Castillo… - Academic radiology, 2012 - Elsevier
RATIONALE AND OBJECTIVES: Pulmonary functional imaging using four-dimensional x-ray
computed tomographic (4DCT) imaging and hyperpolarized 3He magnetic resonance …

Clinical validation of 4-dimensional computed tomography ventilation with pulmonary function test data

D Brennan, L Schubert, Q Diot, R Castillo… - International Journal of …, 2015 - Elsevier
Purpose A new form of functional imaging has been proposed in the form of 4-dimensional
computed tomography (4DCT) ventilation. Because 4DCTs are acquired as part of routine …

Estimating lung ventilation directly from 4D CT Hounsfield unit values

J Kipritidis, MS Hofman, S Siva, J Callahan… - Medical …, 2016 - Wiley Online Library
Purpose: Computed tomography ventilation imaging (CTVI) aims to visualize air‐volume
changes in the lung by quantifying respiratory motion in 4DCT using deformable image …

Development of quantitative computed tomography lung protocols

JD Newell Jr, J Sieren, EA Hoffman - Journal of thoracic imaging, 2013 - journals.lww.com
The purpose of this review article is to review the process of developing optimal computed
tomography (CT) protocols for quantitative lung CT (QCT). In this review, we discuss the …