Acute lymphoblastic leukemia in children
SP Hunger, CG Mullighan - New England Journal of Medicine, 2015 - Mass Medical Soc
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Genetic basis of acute lymphoblastic leukemia
I Iacobucci, CG Mullighan - Journal of Clinical Oncology, 2017 - ascopubs.org
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and despite cure
rates exceeding 90% in children, it remains an important cause of morbidity and mortality in …
rates exceeding 90% in children, it remains an important cause of morbidity and mortality in …
Childhood acute lymphoblastic leukemia: progress through collaboration
CH Pui, JJ Yang, SP Hunger, R Pieters… - Journal of Clinical …, 2015 - ascopubs.org
Purpose To review the impact of collaborative studies on advances in the biology and
treatment of acute lymphoblastic leukemia (ALL) in children and adolescents. Methods A …
treatment of acute lymphoblastic leukemia (ALL) in children and adolescents. Methods A …
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia
KG Roberts, Y Li, D Payne-Turner… - New England journal …, 2014 - Mass Medical Soc
Background Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is
characterized by a gene-expression profile similar to that of BCR–ABL1–positive ALL …
characterized by a gene-expression profile similar to that of BCR–ABL1–positive ALL …
Treatment and biology of pediatric acute lymphoblastic leukemia
M Kato, A Manabe - Pediatrics International, 2018 - Wiley Online Library
Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. In the past
ALL was intractable but now the survival probability is as high as 80–90%. Improved …
ALL was intractable but now the survival probability is as high as 80–90%. Improved …
Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults
N Jain, KG Roberts, E Jabbour, K Patel… - Blood, The Journal …, 2017 - ashpublications.org
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk
subtype of ALL in children. There are conflicting data on the incidence and prognosis of Ph …
subtype of ALL in children. There are conflicting data on the incidence and prognosis of Ph …
Acute lymphoblastic leukaemia
H Inaba, M Greaves, CG Mullighan - The Lancet, 2013 - thelancet.com
Acute lymphoblastic leukaemia occurs in both children and adults but its incidence peaks
between 2 and 5 years of age. Causation is multifactorial and exogenous or endogenous …
between 2 and 5 years of age. Causation is multifactorial and exogenous or endogenous …
[HTML][HTML] Thymic stromal lymphopoietin isoforms, inflammatory disorders, and cancer
G Varricchi, A Pecoraro, G Marone… - Frontiers in …, 2018 - frontiersin.org
Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine originally isolated from a
murine thymic stromal cell line. TSLP exerts its biological effects by binding to a high-affinity …
murine thymic stromal cell line. TSLP exerts its biological effects by binding to a high-affinity …
The emerging complexity of gene fusions in cancer
F Mertens, B Johansson, T Fioretos… - Nature Reviews Cancer, 2015 - nature.com
Structural chromosome rearrangements may result in the exchange of coding or regulatory
DNA sequences between genes. Many such gene fusions are strong driver mutations in …
DNA sequences between genes. Many such gene fusions are strong driver mutations in …
Philadelphia chromosome–like acute lymphoblastic leukemia
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL), also referred to as
BCR-ABL1–like ALL, is a high-risk subset with a gene expression profile that shares …
BCR-ABL1–like ALL, is a high-risk subset with a gene expression profile that shares …