Role of m6A writers, erasers and readers in cancer
Z Fang, W Mei, C Qu, J Lu, L Shang, F Cao… - … Hematology & Oncology, 2022 - Springer
Abstract The N (6)-methyladenosine (m6A) modification is the most pervasive modification of
human RNAs. In recent years, an increasing number of studies have suggested that m6A …
human RNAs. In recent years, an increasing number of studies have suggested that m6A …
The RNA-binding protein HuR in human cancer: A friend or foe?
The RNA-binding proteins (RBPs) are critical trans factors that associate with specific cis
elements present in mRNAs whose stability and translation are subject to regulation. The …
elements present in mRNAs whose stability and translation are subject to regulation. The …
HuR as a molecular target for cancer therapeutics and immune-related disorders
M Majumder, P Chakraborty, S Mohan… - Advanced drug delivery …, 2022 - Elsevier
The control of eukaryotic gene expression occurs at multiple levels, from transcription to
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …
[HTML][HTML] RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer
Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …
[HTML][HTML] Biological adaptations of tumor cells to radiation therapy
A Carlos-Reyes, MA Muñiz-Lino… - Frontiers in …, 2021 - frontiersin.org
Radiation therapy has been used worldwide for many decades as a therapeutic regimen for
the treatment of different types of cancer. Just over 50% of cancer patients are treated with …
the treatment of different types of cancer. Just over 50% of cancer patients are treated with …
AU-rich element RNA binding proteins: at the crossroads of post-transcriptional regulation and genome integrity
A Sidali, V Teotia, NS Solaiman, N Bashir… - International Journal of …, 2021 - mdpi.com
Genome integrity must be tightly preserved to ensure cellular survival and to deter the
genesis of disease. Endogenous and exogenous stressors that impose threats to genomic …
genesis of disease. Endogenous and exogenous stressors that impose threats to genomic …
Therapeutic approaches targeting molecular signaling pathways common to diabetes, lung diseases and cancer
R Raguraman, A Srivastava, A Munshi… - Advanced drug delivery …, 2021 - Elsevier
Diabetes mellitus (DM), is the most common metabolic disease and is characterized by
sustained hyperglycemia. Accumulating evidences supports a strong association between …
sustained hyperglycemia. Accumulating evidences supports a strong association between …
[HTML][HTML] Expression and prognostic values of ARID family members in breast cancer
J Zhang, S Hou, Z You, G Li, S Xu, X Li, X Zhang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Expression and prognostic values of ARID family members in breast cancer - PMC Back to Top
Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …
Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …
Quercetin impairs HuR-driven progression and migration of triple negative breast cancer (TNBC) cells
In the present study, we have explored the prognostic value of HuR gene as well as protein
in breast cancers. Furthermore, we have also investigated the HuR therapeutic relevance in …
in breast cancers. Furthermore, we have also investigated the HuR therapeutic relevance in …
RNA-targeted therapies and high-throughput screening methods
S Zhu, S Rooney, G Michlewski - International Journal of Molecular …, 2020 - mdpi.com
RNA-binding proteins (RBPs) are involved in regulating all aspects of RNA metabolism,
including processing, transport, translation, and degradation. Dysregulation of RNA …
including processing, transport, translation, and degradation. Dysregulation of RNA …