[HTML][HTML] Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods

CR Lee, JH Lee, KS Park, YB Kim, BC Jeong… - Frontiers in …, 2016 - frontiersin.org
The emergence of carbapenem-resistant Gram-negative pathogens poses a serious threat
to public health worldwide. In particular, the increasing prevalence of carbapenem-resistant …

[HTML][HTML] The difficult-to-control spread of carbapenemase producers among Enterobacteriaceae worldwide

P Nordmann, L Poirel - Clinical Microbiology and Infection, 2014 - Elsevier
The spread of carbapenemase producers in Enterobacteriaceae has now been identified
worldwide. Three main carbapenemases have been reported; they belong to three classes …

OXA-48-like β-lactamases: global epidemiology, treatment options, and development pipeline

SE Boyd, A Holmes, R Peck… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

Worldwide dissemination of the NDM‐type carbapenemases in Gram‐negative bacteria

L Dortet, L Poirel, P Nordmann - BioMed research international, 2014 - Wiley Online Library
The emergence of one of the most recently described carbapenemases, namely, the New
Delhi metallo‐lactamase (NDM‐1), constitutes a critical and growingly important medical …

Global dissemination of extensively drug‐resistant carbapenemase‐producing E nterobacteriaceae: clinical perspectives on detection, treatment and infection control

T Tängdén, CG Giske - Journal of internal medicine, 2015 - Wiley Online Library
The prevalence of carbapenem‐resistant Gram‐negative bacilli is on the rise worldwide,
posing a major public health threat. Previously, this was mostly a problem in Pseudomonas …

[PDF][PDF] Klebsiella pneumoniae: characteristics of carbapenem resistance and virulence factors

E Candan, N Aksöz - Acta Biochimica Polonica, 2015 - bibliotekanauki.pl
Klebsiella pneumoniae, known as a major threat to public health, is the most common factor
of nosocomial and community acquired infections. In this study, 50 K. pneumoniae clinical …

[HTML][HTML] Prevalence and incidence of carbapenem-resistant K. pneumoniae colonization: systematic review and meta-analysis

T Tesfa, H Mitiku, M Edae, N Assefa - Systematic reviews, 2022 - Springer
Background Klebsiella pneumoniae is a gram-negative rod belonging to the order
Enterobacterales and having a wide distribution in the environment, including the human …

[HTML][HTML] Understanding the epidemiology of multi-drug resistant gram-negative bacilli in the Middle East using a one health approach

I Dandachi, A Chaddad, J Hanna, J Matta… - Frontiers in …, 2019 - frontiersin.org
In the last decade, extended-spectrum cephalosporin and carbapenem resistant Gram-
negative bacilli (GNB) have been extensively reported in the literature as being …

Antimicrobial resistance in Escherichia coli

M Galindo-Méndez - E. Coli Infections-Importance of Early …, 2020 - books.google.com
In the last decades, antimicrobial resistance has become a global threat to public health
systems worldwide. Among those bacteria that pose the greatest threat to human health …

Ceftazidime-avibactam versus colistin for the treatment of infections due to carbapenem-resistant Enterobacterales: a multicenter cohort study

TA Almangour, L Ghonem, A Aljabri… - Infection and drug …, 2022 - Taylor & Francis
Background The aim of this study was to compare the safety and effectiveness of ceftazidime-
avibactam (CAZ-AVI) to colistin-based regimen in the treatment of infections caused by …