Metastatic dissemination of solid tumors, a leading cause of cancer-related mortality,
underscores the urgent need for enhanced insights into the molecular and cellular …

The transforming growth factor β (TGF-β) pathway, which is well studied for its ability to
inhibit cell proliferation in early stages of tumorigenesis while promoting epithelial …

Long non-coding RNAs (lncRNAs) are involved in the pathology of various tumors, including
colorectal cancer (CRC). The crosstalk between carcinoma-associated fibroblasts (CAFs) …

Lung cancer (LC) is the most common cancer-related death globally, and many efforts have
been made to improve the patient care of LC patients, as well as the development of efficient …

Shikonin is the major bioactive component extracted from the roots of Lithospermum
erythrorhizon which is also known as “Zicao” in Traditional Chinese Medicine (TCM). Recent …

Background Oxaliplatin resistance is a major challenge for treatment of advanced colorectal
cancer (CRC). Both acquisition of epithelial-mesenchymal transition (EMT) and suppressed …

Cancer metastasis is responsible for the vast majority of cancer‐related deaths worldwide. In
contrast to numerous discoveries that reveal the detailed mechanisms leading to the …

Dysregulation of long noncoding RNAs (lncRNAs) plays important roles in carcinogenesis
and tumor progression, including hepatocellular carcinoma (HCC). Small nucleolar RNA …

Background Anti-angiogenic therapy represents a promising strategy for non-small-cell lung
cancer (NSCLC) but its application in lung squamous cell carcinoma (SQC) is limited due to …

Increasing evidence has indicated that circular RNAs (circRNAs) play a critical role in cancer
development. However, only a small number of circRNAs have been experimentally …