Colon cancer is a serious health problem across the globe with various dietary lifestyle
modifications. It arises as an inflammation mediated crypts in the colon epithelial cells and …

Simple Summary Pyroptosis is a kind of programmed cell death, which is characterized by
pore formation in the plasma membrane and the release of large amounts of inflammatory …

The NLR family pyrin domain containing 3 (NLRP3) promotes the growth of colorectal
cancer (CRC). However, the therapeutic effect of NLRP3 inhibition on CRC cell progression …

PFAS (per-and polyfluoroalkyl substances) are organofluorine substances that are used
commercially in products like non-stick cookware, food packaging, personal care products …

Inflammasomes contribute to colorectal cancer signaling by primarily inducing inflammation
in the surrounding tumor microenvironment. Its role in inflammation is receiving increasing …

Simple Summary Despite the reduced death rate that comes with improved HIV treatment,
chances of developing cancers in HIV infected individuals remains high. The main culprit …

Background Circulating cytokines have been associated with colorectal cancer (CRC).
However, their causal correlation remains undetermined. This investigation uses genetic …

Background & aims Insulin resistance and chronic inflammation have been reported in
patients with cancer. However, many of the underlying mechanisms and associations are yet …

For the past decades, inflammatory signals have been considered a possible key for
pharmacological interventions. There are several compounds and/or molecules that have …

The advancement of HIV treatment has led to increased life expectancy. However, people
living with HIV (PLWH) are at a higher risk of developing colorectal cancers. Chronic …