Carbonic anhydrases in metazoan model organisms: molecules, mechanisms, and physiology
During the past three decades, mice, zebrafish, fruit flies, and Caenorhabditis elegans have
been the primary model organisms used for the study of various biological phenomena …
been the primary model organisms used for the study of various biological phenomena …
Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?
V Alterio, A Di Fiore, K D'Ambrosio, CT Supuran… - Chemical …, 2012 - ACS Publications
Carbonic anhydrases (CAs, EC 4.2. 1.1) are ubiquitous metallo-enzymes, present
throughout most living organisms and encoded by five evolutionarily unrelated gene …
throughout most living organisms and encoded by five evolutionarily unrelated gene …
Recent advances in the medicinal chemistry of carbonic anhydrase inhibitors
Abstract Carbonic anhydrase (CA, EC 4.2. 1.1) is an enzyme and a very omnipresent zinc
metalloenzyme which catalyzed the reversible hydration and dehydration of carbon dioxide …
metalloenzyme which catalyzed the reversible hydration and dehydration of carbon dioxide …
Characterization of a novel chicken muscle disorder through differential gene expression and pathway analysis using RNA-sequencing
Background Improvements in poultry production within the past 50 years have led to
increased muscle yield and growth rate, which may be contributing to an increased rate and …
increased muscle yield and growth rate, which may be contributing to an increased rate and …
Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP
J Bystrom, I Evans, J Newson, M Stables… - Blood, The Journal …, 2008 - ashpublications.org
Neutralizing injurious stimuli, proinflammatory mediator catabolism, and polymorphonuclear
leukocyte (PMN) clearance are determinants of inflammatory resolution. To this, we recently …
leukocyte (PMN) clearance are determinants of inflammatory resolution. To this, we recently …
[HTML][HTML] Meat quality traits and proteome profile of woody broiler breast (pectoralis major) meat
Woody breast meat has recently become prevalent in the broiler industry in both the United
States and European Union. Recent publications have described the meat quality …
States and European Union. Recent publications have described the meat quality …
Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells
Single-cell sequencing technologies have revealed an unexpectedly broad repertoire of
cells required to mediate complex functions in multicellular organisms. Despite the multiple …
cells required to mediate complex functions in multicellular organisms. Despite the multiple …
The carbonate radical and related oxidants derived from bicarbonate buffer
DB Medinas, G Cerchiaro, DF Trindade… - IUBMB life, 2007 - Wiley Online Library
The unequivocal demonstration that the carbonate radical (CO3•‐) is produced from the
reaction between the ubiquitous carbon dioxide and peroxynitrite, renewed the interest in …
reaction between the ubiquitous carbon dioxide and peroxynitrite, renewed the interest in …
Pepsin in nonacidic refluxate can damage hypopharyngeal epithelial cells
N Johnston, CW Wells, TL Samuels… - Annals of Otology …, 2009 - journals.sagepub.com
Objectives: Studies using combined multichannel intraluminal impedance with pH
monitoring reveal a role for nonacidic reflux in laryngopharyngeal symptoms and injury. We …
monitoring reveal a role for nonacidic reflux in laryngopharyngeal symptoms and injury. We …
Proteomic analysis of membrane-associated proteins from rat liver autophagosomes
A Øverbye, MF Brinchmann, PO Seglen - Autophagy, 2007 - Taylor & Francis
Proteins associated with membranes from purified rat liver autophagosomes were separated
by two-dimensional (2D) gel electrophoresis (zoom gels, pI 4-7 and 6-9), silver-stained and …
by two-dimensional (2D) gel electrophoresis (zoom gels, pI 4-7 and 6-9), silver-stained and …