Introduction: The close relationship existing between aging and thrombosis has growingly
been studied in this last decade. The age‐related development of a prothrombotic …

The link between plasminogen activator inhibitor (PAI)-1 and the metabolic syndrome with
obesity was established many years ago. Increased PAI-1 level can be now considered a …

The rapid increase in the prevalence and severity of obesity in children is likely to lower the
age of onset and increase the incidence of cardiovascular disease worldwide …

The notion that fibrinogen is strongly, consistently, and independently related to
cardiovascular risk has been widely accepted. The evidence is based on numerous …

Recent large clinical trials have demonstrated that HMG-CoA reductase inhibitors, or statins,
markedly reduce morbidity and mortality when used in the primary and secondary …

Background. Different soluble molecules involved in inflammation, endothelial damage, or
hemostasis are recognized as potential cardiovascular risk markers. Studies to assess the …

Polycystic ovary syndrome (PCOS) is a heterogeneous disorder that affects 4% to 7% of
women of reproductive age. 26, 35 In clinical practice, women with PCOS are seen primarily …

Carotid intima-media thickness (IMT), an indicator of atherosclerosis and coronary heart
disease (CHD) is usually evaluated by eye measurement under B-scope carotid artery …

Objective—The purpose of this study was to investigate the effects of plasminogen activator
inhibitor-1 (PAI-1) gene (SERPINE1) single nucleotide polymorphisms (SNPs) on the risk of …

Several studies have found an association between high plasminogen activator inhibitor-1
(PAI-1) levels and myocardial infarction. Whether this is causal or a consequence of …