The possible link between hIAPP accumulation and β-cell death in diabetic patients has
inspired numerous studies focusing on amyloid structures and aggregation pathways of this …

It has long been axiomatic that a protein's structure determines its function. Intrinsically
disordered proteins (IDPs) and disordered protein regions (IDRs) defy this structure …

Peptide-based supramolecular assemblies are a promising class of nanomaterials with
important biomedical applications, specifically in drug delivery and tissue regeneration …

Tubular nanostructures are suggested to have a wide range of applications in
nanotechnology. We report our observation of the self-assembly of a very short peptide, the …

Amyloid fibril formation is assumed to be the molecular basis for a variety of diseases of
unrelated origin. Despite its fundamental clinical importance, the mechanism of amyloid …

Background Protein aggregation correlates with the development of several debilitating
human disorders of growing incidence, such as Alzheimer's and Parkinson's diseases. On …

The formation of well‐ordered fibrillar protein deposits is common to a large group of
amyloid‐associated disorders. This group consists of several major human diseases such …

Over the past several decades, rapid advances have been made in the application of
nanomaterials in the biomedical field including bioimaging and drug delivery. Owing to the …

In order for any biological system to function effectively, it is essential to avoid the inherent
tendency of proteins to aggregate and form potentially harmful deposits,,,. In each of the …

Hydrogels comprise a class of soft materials which are extremely useful in a number of
contexts, for example as matrix-mimetic biomaterials for applications in regenerative …