New developments in the diagnosis and treatment of thyroid cancer

DF Schneider, H Chen - CA: a cancer journal for clinicians, 2013 - Wiley Online Library
Answer questions and earn CME/CNE Thyroid cancer exists in several forms. Differentiated
thyroid cancers include those with papillary and follicular histologies. These tumors exist …

Hürthle cell carcinoma: current perspectives

S Ahmadi, M Stang, XS Jiang, JA Sosa - OncoTargets and therapy, 2016 - Taylor & Francis
Hürthle cell carcinoma (HCC) can present either as a minimally invasive or as a widely
invasive tumor. HCC generally has a more aggressive clinical behavior compared with the …

Thyroid nodules (≥ 4 cm): can ultrasound and cytology reliably exclude cancer?

LI Wharry, KL McCoy, MT Stang, MJ Armstrong… - World journal of …, 2014 - Springer
Background Whether a threshold nodule size should prompt diagnostic thyroidectomy
remains controversial. We examined a consecutive series of patients who all had …

Molecular alterations in Hürthle cell nodules and preoperative cancer risk

WR Doerfler, AV Nikitski, EM Morariu… - Endocrine-related …, 2021 - erc.bioscientifica.com
Hürthle cell carcinoma (HCC) is a distinct type of thyroid cancer genetically characterized by
DNA copy number alterations (CNA), typically of genome haploidization type (GH-type) …

Prevalence and risk factors for thyroid cancer in patients with multinodular goitre

K Apostolou, V Zivaljevic, K Tausanovic, G Zoric… - BJS open, 2021 - academic.oup.com
Background Rates of thyroid cancer in patients with multinodular goitre (MNG) vary widely,
from 3 per cent in older studies to 35 per cent in more recent studies. The purpose of the …

Somatostatin receptor type 2 and thyroid-stimulating hormone receptor expression in oncocytic thyroid neoplasms: Implications for prognosis and treatment

A Gillis, R Zheng-Pywell, C McLeod, D Wang, JM Ness… - Modern Pathology, 2023 - Elsevier
Abstract Somatostatin receptor type 2 (SSTR2) and thyroid-stimulating hormone receptor
(TSHR) display variable expression in primary thyroid tumors and have been implicated as …

The significance of Hürthle cells in thyroid disease

J Cannon - The oncologist, 2011 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to:
Enumerate the variable thyroid pathological conditions in which Hürthle cells are seen and …

Hürthle cell carcinoma of the thyroid gland: systematic review and meta-analysis

A Coca-Pelaz, JP Rodrigo, JP Shah, A Sanabria… - Advances in …, 2021 - Springer
Introduction Hürthle cell carcinoma (HCC) comprises about 5% of thyroid carcinoma cases.
Partly because of its rarity there is much we still need to know about HCC as compared to …

The presence of Hürthle cells does not increase the risk of malignancy in most Bethesda categories in thyroid fine-needle aspirates

Y Ren, N Kyriazidis, WC Faquin, S Soylu, D Kamani… - Thyroid, 2020 - liebertpub.com
Background: Hürthle cell/oncocytic change is commonly reported on thyroid fine-needle
aspiration (FNA) and may be considered an “atypical cell” by clinicians. This study aims to …

Bethesda category III, IV, and V thyroid nodules: can nodule size help predict malignancy?

CM Kiernan, CC Solórzano - Journal of the American College of Surgeons, 2017 - Elsevier
Background The association of tumor size with malignancy in thyroid nodules with
indeterminate cytology (atypia of undetermined significance [AUS]/follicular lesion of …