The growing understanding of RNA functions and their crucial roles in diseases promotes
the application of various RNAs to selectively function on hitherto “undruggable” proteins …

Alzheimer's disease (AD) is the most common neurodegenerative disorder seen in age-
dependent dementia. There is currently no effective treatment for AD, which may be …

With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …

Iron is an essential trace metal for almost all organisms, including human; however,
oxidative stress can easily be caused when iron is in excess, producing toxicity to the human …

Neurodegenerative diseases represent some of the most devastating neurological
disorders, characterized by progressive loss of the structure and function of neurons. Current …

Enhancing neurogenesis within the hippocampal dentate gyrus (DG) is critical for
maintaining brain development and function in many neurological diseases. However, the …

Despite tremendous advances in modern medicine, effective prevention or therapeutic
strategies for age-related neurodegenerative diseases such as Alzheimer's disease (AD) …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with loss of cognitive,
executive, and other mental functions, and is the most common form of age-related …

The drug efflux transporters ABCB1 and ABCG2 at the blood-brain barrier limit the delivery
of drugs into the brain. Strategies to overcome ABCB1/ABCG2 have been largely …

Alzheimer's disease (AD) is a chronic neurodegenerative disorder that is accompanied by
deficits in memory and cognitive functions. The disease is pathologically characterised by …