Electrospun polymer micro/nanofibers as pharmaceutical repositories for healthcare

X Feng, J Li, X Zhang, T Liu, J Ding, X Chen - Journal of Controlled …, 2019 - Elsevier
Electrospun polymer micro/nanofibers have been widely explored as platforms for controlled
delivery of therapeutic agents. Electrospun fibers are featured by large surface area, high …

Tissue engineering tools for modulation of the immune response

RM Boehler, JG Graham, LD Shea - Biotechniques, 2011 - Taylor & Francis
Tissue engineering scaffolds have emerged as a powerful tool within regenerative medicine.
These materials are being designed to create environments that promote regeneration …

An injectable hybrid hydrogel with oriented short fibers induces unidirectional growth of functional nerve cells

A Omidinia‐Anarkoli, S Boesveld, U Tuvshindorj… - small, 2017 - Wiley Online Library
To regenerate soft aligned tissues in living organisms, low invasive biomaterials are
required to create 3D microenvironments with a structural complexity to mimic the tissue's …

Silk hydrogels as soft substrates for neural tissue engineering

AM Hopkins, L De Laporte, F Tortelli… - Advanced functional …, 2013 - Wiley Online Library
There is great need for soft biomaterials that match the stiffness of human tissues for tissue
engineering and regeneration. Hydrogels are frequently employed for extracellular matrix …

Non-viral gene delivery systems for tissue repair and regeneration

P Wu, H Chen, R Jin, T Weng, JK Ho, C You… - Journal of translational …, 2018 - Springer
Critical tissue defects frequently result from trauma, burns, chronic wounds and/or surgery.
The ideal treatment for such tissue loss is autografting, but donor sites are often limited …

[HTML][HTML] Biofunctionalized aligned microgels provide 3D cell guidance to mimic complex tissue matrices

JC Rose, DB Gehlen, T Haraszti, J Köhler, CJ Licht… - Biomaterials, 2018 - Elsevier
Natural healing is based on highly orchestrated processes, in which the extracellular matrix
plays a key role. To resemble the native cell environment, we introduce an artificial …

Emerging links between surface nanotechnology and endocytosis: impact on nonviral gene delivery

AF Adler, KW Leong - Nano today, 2010 - Elsevier
Significant effort continues to be exerted toward the improvement of transfection mediated by
nonviral vectors. These endeavors are often focused on the design of particulate carriers …

Co-effects of matrix low elasticity and aligned topography on stem cell neurogenic differentiation and rapid neurite outgrowth

S Yao, X Liu, S Yu, X Wang, S Zhang, Q Wu, X Sun… - Nanoscale, 2016 - pubs.rsc.org
The development of novel biomaterials that deliver precise regulatory signals to direct stem
cell fate for nerve regeneration is the focus of current intensive research efforts. In this study …

[HTML][HTML] Anisotropic 3D scaffolds for spinal cord guided repair: Current concepts

JPM Sousa, E Stratakis, J Mano, PAAP Marques - Biomaterials Advances, 2023 - Elsevier
A spinal cord injury (SCI) can be caused by unforeseen events such as a fall, a vehicle
accident, a gunshot, or a malignant illness, which has a significant impact on the quality of …

Engineering biomaterial systems to enhance viral vector gene delivery

JH Jang, DV Schaffer, LD Shea - Molecular therapy, 2011 - cell.com
Integrating viral gene delivery with engineered biomaterials is a promising strategy to
overcome a number of challenges associated with virus-mediated gene delivery, including …