5-Amino-pyrazoles: potent reagents in organic and medicinal synthesis
Amino-pyrazoles have proven to be a class of fascinating and privileged organic tools for the
construction of diverse heterocyclic or fused heterocyclic scaffolds. This review presents …
construction of diverse heterocyclic or fused heterocyclic scaffolds. This review presents …
Advances in the chemical and biological diversity of heterocyclic systems incorporating pyrimido [1, 6-a] pyrimidine and pyrimido [1, 6-c] pyrimidine scaffolds
Heterocycles incorporating a pyrimidopyrimidine scaffold have aroused great interest from
researchers in the field of medical chemistry because of their privileged biological activities; …
researchers in the field of medical chemistry because of their privileged biological activities; …
Synthesis and antitumor activity of some new pyrazolo [1, 5-a] pyrimidines
Abstract New series of pyrazolo [1, 5-a] pyrimidine derivatives 7a–i, 11a–c and Schiff bases
13a–c were synthesized and screened for their in vitro antitumor activity against three …
13a–c were synthesized and screened for their in vitro antitumor activity against three …
Synthesis and anti-tumor activities of some new pyridines and pyrazolo [1, 5-a] pyrimidines
Cyclocondensation of cyanoacetamide, cyanothioacetamide and 3-aminopyrazols with
sodium salt of 3-hydroxy-1-(2-naphthyl) prop-2-en-1-one gives pyridin-2-one, pyridin-2 (1H) …
sodium salt of 3-hydroxy-1-(2-naphthyl) prop-2-en-1-one gives pyridin-2-one, pyridin-2 (1H) …
Trifluoromethyl-substituted aryldiazenyl-pyrazolo [1, 5-a] pyrimidin-2-amines: Regioselective synthesis, structure, and optical properties
FS Stefanello, YG Kappenberg, JN Araujo… - Journal of Fluorine …, 2022 - Elsevier
This paper describes for the first time an efficient approach to synthesize a novel
trifluoromethylated heterocyclic system of seventeen examples of substituted …
trifluoromethylated heterocyclic system of seventeen examples of substituted …
Design, synthesis, docking, and antimicrobial evaluation of some novel pyrazolo[1,5-a] pyrimidines and their corresponding cycloalkane ring-fused derivatives as …
AEM Abdallah, GH Elgemeie - drug design, development and …, 2018 - Taylor & Francis
Background Over the years, pyrazolopyrimidine derivatives have been recognized as
having antimicrobial activities. Recently, we reported different synthetic methods to prepare …
having antimicrobial activities. Recently, we reported different synthetic methods to prepare …
Convenient method for synthesis of various fused heterocycles via utility of 4-acetyl-5-methyl-1-phenyl-pyrazole as precursor
SM Gomha, AS Shawali… - Turkish Journal of …, 2014 - journals.tubitak.gov.tr
A new, less expensive, solvent-free procedure was developed for the synthesis of some new
derivatives of various fused heterocyclic ring systems, namely azolopyridazine …
derivatives of various fused heterocyclic ring systems, namely azolopyridazine …
Compounds useful as inhibitors of ATR kinase
N Ahmad, D Boyall, JD Charrier, C Davis… - US Patent …, 2016 - Google Patents
2015-09-14 Assigned to VERTEX PHARMACEUTICALS (EUROPE) LIMITED reassignment
VERTEX PHARMACEUTICALS (EUROPE) LIMITED ASSIGNMENT OF ASSIGNORS …
VERTEX PHARMACEUTICALS (EUROPE) LIMITED ASSIGNMENT OF ASSIGNORS …
New route to the synthesis of Benzamide-Based 5-aminopyrazoles and their fused heterocycles showing remarkable antiavian influenza virus activity
This study describes a new route to the synthesis of novel benzamide-based 5-
aminopyrazoles and their corresponding pyrazolo [1, 5-a] pyrimidine and pyrazolo [5, 1-c][1 …
aminopyrazoles and their corresponding pyrazolo [1, 5-a] pyrimidine and pyrazolo [5, 1-c][1 …
Efficient Synthesis and Antimicrobial Evaluation of New Azolopyrimidines‐Bearing Pyrazole Moiety
AO Abdelhamid, SM Gomha… - Journal of Heterocyclic …, 2019 - Wiley Online Library
Sodium salt of 3‐hydroxy‐1‐(1‐aryl‐5‐methylpyrazolyl) propenone derivatives was used as
a precursor for synthesis of various fused azolopyrimidine ring systems as …
a precursor for synthesis of various fused azolopyrimidine ring systems as …