Decoding signalling networks by mass spectrometry-based proteomics
C Choudhary, M Mann - Nature reviews Molecular cell biology, 2010 - nature.com
Signalling networks regulate essentially all of the biology of cells and organisms in normal
and disease states. Signalling is often studied using antibody-based techniques such as …
and disease states. Signalling is often studied using antibody-based techniques such as …
[HTML][HTML] Proliferation and fission of peroxisomes—An update
In mammals, peroxisomes perform crucial functions in cellular metabolism, signalling and
viral defense which are essential to the health and viability of the organism. In order to …
viral defense which are essential to the health and viability of the organism. In order to …
The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices
The extracellular matrix (ECM) is a complex meshwork of cross-linked proteins providing
both biophysical and biochemical cues that are important regulators of cell proliferation …
both biophysical and biochemical cues that are important regulators of cell proliferation …
The one hour yeast proteome
We describe the comprehensive analysis of the yeast proteome in just over one hour of
optimized analysis. We achieve this expedited proteome characterization with improved …
optimized analysis. We achieve this expedited proteome characterization with improved …
A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics
MaxQuant is a quantitative proteomics software package designed for analyzing large mass
spectrometric data sets. It is specifically aimed at high-resolution mass spectrometry (MS) …
spectrometric data sets. It is specifically aimed at high-resolution mass spectrometry (MS) …
Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization
LRRK2 (leucine-rich repeat protein kinase 2) is mutated in a significant number of
Parkinson's disease patients. Since a common mutation that replaces Gly2019 with a serine …
Parkinson's disease patients. Since a common mutation that replaces Gly2019 with a serine …
PHOSIDA 2011: the posttranslational modification database
The primary purpose of PHOSIDA (http://www. phosida. com) is to manage posttranslational
modification sites of various species ranging from bacteria to human. Since its last report …
modification sites of various species ranging from bacteria to human. Since its last report …
[图书][B] Mammalian transient receptor potential (TRP) cation channels
B Nilius, V Flockerzi - 2014 - Springer
When we edited in 2007 the first issue on transient receptor potential channel in the
Handbook of Experimental Pharmacology, we were all very excited by the progress in this …
Handbook of Experimental Pharmacology, we were all very excited by the progress in this …
Exploring the caves: cavins, caveolins and caveolae
CG Hansen, BJ Nichols - Trends in cell biology, 2010 - cell.com
Caveolae are ampullate (flask-shaped) invaginations that are abundant in the plasma
membrane of many mammalian cell types. Although caveolae are implicated in a wide …
membrane of many mammalian cell types. Although caveolae are implicated in a wide …
Proteome, phosphoproteome, and N-glycoproteome are quantitatively preserved in formalin-fixed paraffin-embedded tissue and analyzable by high-resolution mass …
P Ostasiewicz, DF Zielinska, M Mann… - Journal of proteome …, 2010 - ACS Publications
Tissue samples in biobanks are typically formalin-fixed and paraffin-embedded (FFPE), in
which form they are preserved for decades. It has only recently been shown that proteins in …
which form they are preserved for decades. It has only recently been shown that proteins in …