[HTML][HTML] Iron in infection and immunity
M Nairz, G Weiss - Molecular Aspects of Medicine, 2020 - Elsevier
Iron is an essential micronutrient for virtually all living cells. In infectious diseases, both
invading pathogens and mammalian cells including those of the immune system require iron …
invading pathogens and mammalian cells including those of the immune system require iron …
Human genetics and malaria resistance
SN Kariuki, TN Williams - Human genetics, 2020 - Springer
Malaria has been the pre-eminent cause of early mortality in many parts of the world
throughout much of the last five thousand years and, as a result, it is the strongest force for …
throughout much of the last five thousand years and, as a result, it is the strongest force for …
Pathophysiology and neurologic sequelae of cerebral malaria
N Schiess, A Villabona-Rueda, KE Cottier, K Huether… - Malaria journal, 2020 - Springer
Cerebral malaria (CM), results from Plasmodium falciparum infection, and has a high
mortality rate. CM survivors can retain life-long post CM sequelae, including seizures and …
mortality rate. CM survivors can retain life-long post CM sequelae, including seizures and …
Red blood cell tension protects against severe malaria in the Dantu blood group
SN Kariuki, A Marin-Menendez, V Introini, BJ Ravenhill… - Nature, 2020 - nature.com
Malaria has had a major effect on the human genome, with many protective polymorphisms—
such as the sickle-cell trait—having been selected to high frequencies in malaria-endemic …
such as the sickle-cell trait—having been selected to high frequencies in malaria-endemic …
Evaluating the promise of inclusion of African ancestry populations in genomics
AR Bentley, SL Callier, CN Rotimi - NPJ genomic medicine, 2020 - nature.com
The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …
known, and the resultant scientific and ethical limitations are becoming increasingly …
Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania
Nature communications, 2019 - nature.com
The human genetic factors that affect resistance to infectious disease are poorly understood.
Here we report a genome-wide association study in 17,000 severe malaria cases and …
Here we report a genome-wide association study in 17,000 severe malaria cases and …
Improving the diagnosis of severe malaria in African children using platelet counts and plasma PfHRP2 concentrations
Severe malaria caused by Plasmodium falciparum is difficult to diagnose accurately in
children in high-transmission settings. Using data from 2649 pediatric and adult patients …
children in high-transmission settings. Using data from 2649 pediatric and adult patients …
Tracing Bai-Yue ancestry in aboriginal Li people on hainan island
As the most prevalent aboriginal group on Hainan Island located between South China and
the mainland of Southeast Asia, the Li people are believed to preserve some unique genetic …
the mainland of Southeast Asia, the Li people are believed to preserve some unique genetic …
Pathogenicity and virulence of malaria: Sticky problems and tricky solutions
IS Walker, SJ Rogerson - Virulence, 2023 - Taylor & Francis
Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …
each year, concentrated in Africa and in young children, but much of the world's population …
Erythrocyte glycophorins as receptors for Plasmodium merozoites
E Jaskiewicz, M Jodłowska, R Kaczmarek, A Zerka - Parasites & vectors, 2019 - Springer
Glycophorins are heavily glycosylated sialoglycoproteins of human and animal erythrocytes.
In humans, there are four glycophorins: A, B, C and D. Glycophorins play an important role in …
In humans, there are four glycophorins: A, B, C and D. Glycophorins play an important role in …