In the past 37 years, human immunodeficiency virus/acquired immunodeficiency syndrome
(HIV/AIDS) has undergone various major transmission routes in China, with the world most …

Introduction: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are essential
components of highly active antiretroviral therapy against HIV-1 infections. Here, we provide …

Importance New data and therapeutic options warrant updated recommendations for the use
of antiretroviral drugs (ARVs) to treat or to prevent HIV infection in adults. Objective To …

Background Contemporary antiretroviral therapies (ART) and management strategies have
diminished both human immunodeficiency virus (HIV) treatment failure and the acquired …

The 2019 edition of the IAS-USA drug resistance mutations list updates the Figure last
published in January 2017. The mutations listed are those that have been identified by …

Background We evaluated the prevalence of transmitted drug resistance (TDR) to integrase
strand-transfer inhibitors (INSTIs) and nucleoside/nucleotide reverse transcriptase inhibitors …

Drug resistant HIV is a major threat to the long-term efficacy of antiretroviral treatment.
Around 10% of ART-naïve patients in Europe are infected with drug-resistant HIV type 1 …

This manuscript reviews the reasons why Integrase inhibitors should now routinely
constitute a part of first line antiretroviral therapy for the treatment of HIV disease. The use of …

Background Eastern Europe and Central Asia (EECA) is one of the regions where the HIV
epidemic continues to grow at a concerning rate. Antiretroviral therapy (ART) coverage in …

Background: Over 90% of Human Immunodeficiency Virus (HIV) infected individuals will be
on treatment by 2020under UNAIDS 90-90-90 global targets. Under World Health …