Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease

C Borghi, E Agabiti-Rosei, RJ Johnson… - European journal of …, 2020 - Elsevier
During the last century, there has been an increasing prevalence of hyperuricaemia noted in
many populations. While uric acid is usually discussed in the context of gout …

Uric acid and hypertension: a review of evidence and future perspectives for the management of cardiovascular risk

C Borghi, D Agnoletti, AFG Cicero, E Lurbe… - Hypertension, 2022 - Am Heart Assoc
Uric acid is the final product of purine metabolism, and its increased serum levels have been
directly involved in the pathogenesis and natural history of hypertension. The relationship …

Uric acid in metabolic syndrome: from an innocent bystander to a central player

M Kanbay, T Jensen, Y Solak, M Le… - European journal of …, 2016 - Elsevier
Uric acid, once viewed as an inert metabolic end-product of purine metabolism, has been
recently incriminated in a number of chronic disease states, including hypertension …

Uric acid is a strong risk marker for developing hypertension from prehypertension: a 5-year Japanese cohort study

M Kuwabara, I Hisatome, K Niwa, S Hara… - …, 2018 - Am Heart Assoc
Prehypertension frequently progresses to hypertension, a condition associated with high
morbidity and mortality from cardiovascular diseases and stroke. However, the risk factors …

Uric acid and the cardio‐renal effects of SGLT2 inhibitors

CJ Bailey - Diabetes, Obesity and Metabolism, 2019 - Wiley Online Library
Sodium/glucose co‐transporter‐2 (SGLT2) inhibitors, which lower blood glucose by
increasing renal glucose elimination, have been shown to reduce the risk of adverse …

Hyperuricemia and cardiovascular disease

S Zhang, Y Wang, J Cheng, N Huangfu… - Current …, 2019 - ingentaconnect.com
Purine metabolism in the circulatory system yields uric acid as its final oxidation product,
which is believed to be linked to the development of gout and kidney stones. Hyperuricemia …

Hyperuricemia and risk of cardiovascular outcomes: the experience of the URRAH (uric acid right for heart health) project

A Maloberti, C Giannattasio, M Bombelli… - High Blood Pressure & …, 2020 - Springer
Abstract The latest European Guidelines of Arterial Hypertension have officially introduced
uric acid evaluation among the cardiovascular risk factors that should be evaluated in order …

Expert consensus for the diagnosis and treatment of patient with hyperuricemia and high cardiovascular risk

C Borghi, A Tykarski, K Widecka, KJ Filipiak… - Cardiology …, 2018 - journals.viamedica.pl
The definition of hyperuricemia (HU) varies widely in different studies, which makes the
epidemiological reports somewhat inconsistent. HU remains the culprit of the pathogenesis …

Hyperuricemia and hypertension: links and risks

DJ Stewart, V Langlois, D Noone - Integrated blood pressure …, 2019 - Taylor & Francis
Hyperuricemia has long been recognized to be associated with increased cardiovascular
risk, including risk of developing hypertension. Epidemiological findings suggest that the link …

[HTML][HTML] The role of uric acid in acute and chronic coronary syndromes

A Maloberti, M Biolcati, G Ruzzenenti, V Giani… - Journal of Clinical …, 2021 - mdpi.com
Uric acid (UA) is the final product of the catabolism of endogenous and exogenous purine
nucleotides. While its association with articular gout and kidney disease has been known for …