Natural and targeted circuit reorganization after spinal cord injury

MA Anderson, JW Squair, M Gautier, TH Hutson… - Nature …, 2022 - nature.com
A spinal cord injury disrupts communication between the brain and the circuits in the spinal
cord that regulate neurological functions. The consequences are permanent paralysis, loss …

[HTML][HTML] Stem cell-derived neuronal relay strategies and functional electrical stimulation for treatment of spinal cord injury

BQ Lai, X Zeng, WT Han, MT Che, Y Ding, G Li… - Biomaterials, 2021 - Elsevier
The inability of adult mammals to recover function lost after severe spinal cord injury (SCI)
has been known for millennia and is mainly attributed to a failure of brain-derived nerve fiber …

Movement is governed by rotational neural dynamics in spinal motor networks

H Lindén, PC Petersen, M Vestergaard, RW Berg - Nature, 2022 - nature.com
Although the generation of movements is a fundamental function of the nervous system, the
underlying neural principles remain unclear. As flexor and extensor muscle activities …

Electrical stimulation for therapeutic approach

E Kim, S Kim, YW Kwon, H Seo, M Kim… - Interdisciplinary …, 2023 - Wiley Online Library
Electrical stimulation as a therapeutic approach is widely applicable in terms of target
tissues or target effects. This method can be an alternative to conventional therapies for …

[HTML][HTML] Recent advances in the application of MXenes for neural tissue engineering and regeneration

M Liao, Q Cui, Y Hu, J Xing, D Wu… - Neural Regeneration …, 2024 - journals.lww.com
Transition metal carbides and nitrides (MXenes) are crystal nanomaterials with a number of
surface functional groups such as fluorine, hydroxyl, and oxygen, which can be used as …

Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury

A Aljović, A Jacobi, M Marcantoni, F Kagerer… - EMBO Molecular …, 2023 - embopress.org
Functional recovery following incomplete spinal cord injury (SCI) depends on the rewiring of
motor circuits during which supraspinal connections form new contacts onto spinal relay …

The mesencephalic locomotor region: multiple cell types, multiple behavioral roles, and multiple implications for disease

D Ryczko - The Neuroscientist, 2024 - journals.sagepub.com
The mesencephalic locomotor region (MLR) controls locomotion in vertebrates. In humans
with Parkinson disease, locomotor deficits are increasingly associated with decreased …

Invasive brain computer interface for motor restoration in spinal cord injury: a systematic review

JJ Levett, LM Elkaim, F Niazi, MH Weber… - … : Technology at the …, 2023 - Elsevier
Study design Systematic review of the literature. Objectives In recent years, brain-computer
interface (BCI) has emerged as a potential treatment for patients with spinal cord injury …

Bibliometric analysis of stem cells for spinal cord injury: current status and emerging frontiers

Z Shang, P Wanyan, M Wang, B Zhang, X Cui… - Frontiers in …, 2023 - frontiersin.org
Background: This study aimed to conduct a bibliometric analysis of the literature on stem cell
therapy for spinal cord injury to visualize the research status, identify hotspots, and explore …

Preclinical upper limb neurorobotic platform to assess, rehabilitate, and develop therapies

M Pasquini, ND James, I Dewany, FV Coen, N Cho… - Science Robotics, 2022 - science.org
Numerous neurorehabilitative, neuroprosthetic, and repair interventions aim to address the
consequences of upper limb impairments after neurological disorders. Although these …