Primary open-angle glaucoma

RN Weinreb, CKS Leung, JG Crowston… - Nature reviews Disease …, 2016 - nature.com
Glaucoma is an optic neuropathy that is characterized by the progressive degeneration of
the optic nerve, leading to visual impairment. Glaucoma is the main cause of irreversible …

Alzheimer's disease and retinal neurodegeneration

L Guo, J Duggan, MF Cordeiro - Current Alzheimer Research, 2010 - ingentaconnect.com
Alzheimer's disease (AD) is the major cause of dementia in the world. Although the
entorhinal cortex and hippocampal complex are best known as the sites of early pathology …

Experimental and clinical evidence of neuroprotection by nerve growth factor eye drops: Implications for glaucoma

A Lambiase, L Aloe, M Centofanti… - Proceedings of the …, 2009 - National Acad Sciences
Elevated intraocular pressure (IOP) in glaucoma causes loss of retinal ganglion cells
(RGCs) and damage to the optic nerve. Although IOP is controlled pharmacologically, no …

Association of blood pressure status with the optic disk structure in non-glaucoma subjects: the Thessaloniki eye study

F Topouzis, AL Coleman, A Harris… - American journal of …, 2006 - Elsevier
PURPOSE: To study the association of blood pressure (BP) status on the optic disk structure
as measured with the Heidelberg Retina Tomograph (HRT) in people without glaucoma …

Neurodegeneration in glaucoma: progression and calcium-dependent intracellular mechanisms

SD Crish, DJ Calkins - Neuroscience, 2011 - Elsevier
Glaucoma is an age-related optic neuropathy involving sensitivity to ocular pressure. The
disease is now seen increasingly as one of the central nervous system, as powerful new …

Geographic atrophy in patients with advanced dry age-related macular degeneration: current challenges and future prospects

RP Danis, JA Lavine, A Domalpally - Clinical Ophthalmology, 2015 - Taylor & Francis
Geographic atrophy (GA) of the retinal pigment epithelium (RPE) is a devastating
complication of age-related macular degeneration (AMD). GA may be classified as drusen …

Immunoregulation of retinal ganglion cell fate in glaucoma

MB Wax, G Tezel - Experimental eye research, 2009 - Elsevier
Glaucomatous neurodegeneration has been associated with the activation of multiple
pathogenic mechanisms that can result in RGC death and axonal degeneration. Growing …

Vision function abnormalities in Alzheimer disease

R Tzekov, M Mullan - Survey of Ophthalmology, 2014 - Elsevier
Alzheimer disease (AD) is a progressive, age-related debilitating condition that is a growing
public health problem in the developed world. Visual system abnormalities in AD were …

[HTML][HTML] Longitudinal evaluation of retinal ganglion cell function and IOP in the DBA/2J mouse model of glaucoma

M Saleh, M Nagaraju, V Porciatti - … ophthalmology & visual …, 2007 - iovs.arvojournals.org
purpose. To characterize progressive changes of retinal ganglion cell (RGC) function and
intraocular pressure (IOP) in the DBA/2J mouse model of spontaneous glaucoma. methods …

Pharmacological neuroprotection for glaucoma

G Chidlow, JPM Wood, RJ Casson - Drugs, 2007 - Springer
Glaucoma represents a group of neurodegenerative diseases characterised by structural
damage to the optic nerve and slow, progressive death of retinal ganglion cells (RGCs) …