Fibrosis denotes excessive scarring, which exceeds the normal wound healing response to
injury in many tissues. Although the extracellular matrix deposition appears unstructured …

Despite recent advances in the management of chronic kidney disease (CKD), morbidity
and mortality rates in these patients remain high. While pressure-mediated injury is a well …

Given the high risk of infection-related mortality, patients with end-stage kidney disease
(ESKD) may be at increased risk with COVID-19. To assess this, we compared outcomes of …

Background COVID-19 is a pandemic disease caused by a novel coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Predictors for severe COVID-19 …

Cardiovascular disease and infections are major causes for the high incidence of morbidity
and mortality of patients with chronic kidney disease. Both complications are directly or …

The kidneys and heart share functions with the common goal of maintaining homeostasis.
When kidney injury occurs, many compounds, the so-called “uremic retention solutes” or …

ATP and its ultimate degradation product adenosine are potent extracellular signalling
molecules that elicit a variety of pathophysiological functions in the kidney through the …

Black solider fly larvae (BSFL) and their oils (BSFLO) are receiving increasing attention as
sustainable ingredients in fish feeds, but mostly as replacements to marine sources. There …

Microglia, the primary immune cells of the central nervous system (CNS), are derived from
the yolk sac and populate the brain during development. Once microglia migrate to the CNS …

Alport syndrome affects up to 60,000 people in the United States. The proposed
reclassification of thin basement membrane nephropathy and some cases of focal …