Metagenomics-enabled microbial surveillance

KKK Ko, KR Chng, N Nagarajan - Nature Microbiology, 2022 - nature.com
Lessons learnt from the COVID-19 pandemic include increased awareness of the potential
for zoonoses and emerging infectious diseases that can adversely affect human health …

A practical guide to amplicon and metagenomic analysis of microbiome data

YX Liu, Y Qin, T Chen, M Lu, X Qian, X Guo… - Protein & cell, 2021 - academic.oup.com
Advances in high-throughput sequencing (HTS) have fostered rapid developments in the
field of microbiome research, and massive microbiome datasets are now being generated …

Oxford Nanopore R10. 4 long-read sequencing enables the generation of near-finished bacterial genomes from pure cultures and metagenomes without short-read or …

M Sereika, RH Kirkegaard, SM Karst, TY Michaelsen… - Nature …, 2022 - nature.com
Abstract Long-read Oxford Nanopore sequencing has democratized microbial genome
sequencing and enables the recovery of highly contiguous microbial genomes from isolates …

A genomic catalog of Earth's microbiomes

S Nayfach, S Roux, R Seshadri, D Udwary… - Nature …, 2021 - nature.com
The reconstruction of bacterial and archaeal genomes from shotgun metagenomes has
enabled insights into the ecology and evolution of environmental and host-associated …

Improved metagenomic analysis with Kraken 2

DE Wood, J Lu, B Langmead - Genome biology, 2019 - Springer
Although Kraken'sk-mer-based approach provides a fast taxonomic classification of
metagenomic sequence data, its large memory requirements can be limiting for some …

A new genomic blueprint of the human gut microbiota

A Almeida, AL Mitchell, M Boland, SC Forster, GB Gloor… - Nature, 2019 - nature.com
The composition of the human gut microbiota is linked to health and disease, but knowledge
of individual microbial species is needed to decipher their biological roles. Despite …

Interrogating the viral dark matter of the rumen ecosystem with a global virome database

M Yan, AA Pratama, S Somasundaram, Z Li… - Nature …, 2023 - nature.com
The diverse rumen virome can modulate the rumen microbiome, but it remains largely
unexplored. Here, we mine 975 published rumen metagenomes for viral sequences, create …

New insights from uncultivated genomes of the global human gut microbiome

S Nayfach, ZJ Shi, R Seshadri, KS Pollard… - Nature, 2019 - nature.com
The genome sequences of many species of the human gut microbiome remain unknown,
largely owing to challenges in cultivating microorganisms under laboratory conditions. Here …

Compendium of 4,941 rumen metagenome-assembled genomes for rumen microbiome biology and enzyme discovery

RD Stewart, MD Auffret, A Warr, AW Walker… - Nature …, 2019 - nature.com
Ruminants provide essential nutrition for billions of people worldwide. The rumen is a
specialized stomach that is adapted to the breakdown of plant-derived complex …

A catalogue of 1,167 genomes from the human gut archaeome

CM Chibani, A Mahnert, G Borrel, A Almeida… - Nature …, 2022 - nature.com
The human gut microbiome plays an important role in health, but its archaeal diversity
remains largely unexplored. In the present study, we report the analysis of 1,167 …