Organoselenium compounds as mimics of selenoproteins and thiol modifier agents

NV Barbosa, CW Nogueira, PA Nogara… - Metallomics, 2017 - academic.oup.com
Selenium is an essential trace element for animals and its role in the chemistry of life relies
on a unique functional group: the selenol (–SeH) group. The selenol group participates in …

Research progress on signaling pathway‐associated oxidative stress in endothelial cells

Y Liang, J Li, Q Lin, P Huang, L Zhang… - … Medicine and Cellular …, 2017 - Wiley Online Library
Studying the mechanisms of oxidative stress in endothelial cells is vital to the discovery of
novel drugs for the treatment of cardiovascular disease. This article reviews the progress …

Naringenin protects cardiac hypercholesterolemia-induced oxidative stress and subsequent necroptosis in rats

Y Chtourou, AB Slima, M Makni, R Gdoura… - Pharmacological …, 2015 - Springer
Background In earlier studies, the supplementation of the natural compound Naringenin
(NGEN), improved the liver oxidative and inflammatory status, which indicates its direct effect …

[HTML][HTML] Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent antioxidant …

RL Quispe, ML Jaramillo, LS Galant, D Engel, AL Dafre… - Redox biology, 2019 - Elsevier
Oxidative stress and mitochondrial dysfunction are critical events in neurodegenerative
diseases; therefore, molecules that increase cellular antioxidant defenses represent a future …

β-caryophyllene reduces atherogenic index and coronary risk index in hypercholesterolemic rats: The involvement of cardiac oxidative damage

MD Baldissera, CF Souza, TH Grando… - Chemico-Biological …, 2017 - Elsevier
Hypercholesterolemia and cardiac oxidative damage have been implicated in the
pathophysiology of atherosclerosis. In earlier studies, treatment using natural …

Bazi Bushen capsule alleviates post-menopausal atherosclerosis via GPER1-dependent anti-inflammatory and anti-apoptotic effects

D Huang, X Wang, Y Zhu, J Gong, J Liang… - Frontiers in …, 2021 - frontiersin.org
Bazi Bushen capsule (BZBS), as a Chinese medicine used to relieve fatigue, has been
proven effective for the treatment of atherogenesis through antilipid effects. To investigate …

Notoginsenoside R1 inhibits oxidized low-density lipoprotein induced inflammatory cytokines production in human endothelial EA. hy926 cells

P Su, S Du, H Li, Z Li, W Xin, W Zhang - European journal of pharmacology, 2016 - Elsevier
Abstract Notoginsenoside R1 (NG-R1), a unique and main active ingredient of Panax
notoginseng, has been described to exhibit anti-inflammatory activity. However, its protective …

Assessment of hypolipidemic, anti-inflammatory and antioxidant properties of medicinal plant Erica multiflora in triton WR-1339-induced hyperlipidemia and liver …

R Khlifi, A Lahmar, Z Dhaouefi, Z Kalboussi… - Regulatory toxicology …, 2019 - Elsevier
Hyperlipidemia is a serious health threat that has been linked to oxidative stress and
systemic inflammation, causing among many other disorders essentially liver disease. The …

(+)‐Catechin Attenuates Multiple Atherosclerosis‐Associated Processes In Vitro, Modulates Disease‐Associated Risk Factors in C57BL/6J Mice and Reduces …

YH Chan, JWE Moss, JO Williams… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope A prospective study of 34492 participants shows an inverse association between (+)‐
catechin intake and coronary heart disease. The effects of (+)‐catechin on atherosclerosis …

Impact of SIN-1-derived peroxynitrite flux on endothelial cell redox homeostasis and bioenergetics: protective role of diphenyl diselenide via induction of …

B Fiuza, N Subelzú, P Calcerrada… - Free radical …, 2015 - Taylor & Francis
Increased production of reactive nitrogen (RNS) and oxygen (ROS) species and its
detrimental effect to mitochondria are associated with endothelial dysfunction. This study …