Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

Methylprednisolone for the treatment of patients with acute spinal cord injuries: a systematic review and meta-analysis

N Evaniew, EP Belley-Côté, N Fallah… - Journal of …, 2016 - liebertpub.com
Previous meta-analyses of methylprednisolone (MPS) for patients with acute traumatic
spinal cord injuries (TSCIs) have not addressed confidence in the quality of evidence used …

Early versus delayed decompression for traumatic cervical spinal cord injury: results of the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS)

MG Fehlings, A Vaccaro, JR Wilson, A Singh… - PloS one, 2012 - journals.plos.org
Background There is convincing preclinical evidence that early decompression in the setting
of spinal cord injury (SCI) improves neurologic outcomes. However, the effect of early …

Diagnosis and prognosis of traumatic spinal cord injury

JJ van Middendorp, B Goss, S Urquhart… - Global spine …, 2011 - journals.sagepub.com
Despite promising advances in basic spinal cord repair research, no effective therapy
resulting in major neurological or functional recovery after traumatic spinal cord injury (tSCI) …

Increasing patient engagement during virtual reality-based motor rehabilitation

L Zimmerli, M Jacky, L Lünenburger, R Riener… - Archives of physical …, 2013 - Elsevier
Objective To investigate the influence of different design characteristics of virtual reality
exercises on engagement during lower extremity motor rehabilitation. Design Correlational …

Extent of spontaneous motor recovery after traumatic cervical sensorimotor complete spinal cord injury

JD Steeves, JK Kramer, JW Fawcett, J Cragg… - Spinal cord, 2011 - nature.com
Study design: Retrospective, longitudinal analysis of motor recovery data from individuals
with cervical (C4–C7) sensorimotor complete spinal cord injury (SCI) according to the …

Functional neurological recovery after spinal cord injury is impaired in patients with infections

V Failli, MA Kopp, C Gericke, P Martus, S Klingbeil… - Brain, 2012 - academic.oup.com
Infections are a common threat to patients after spinal cord injury. Furthermore, infections
might propagate neuronal death, and consequently contribute to the restriction of …

Long-term functional outcome in patients with acquired infections after acute spinal cord injury

MA Kopp, R Watzlawick, P Martus, V Failli… - Neurology, 2017 - AAN Enterprises
Objective: To investigate whether prevalent hospital-acquired pneumonia and wound
infection affect the clinical long-term outcome after acute traumatic spinal cord injury (SCI) …

Assessment of impairment in patients with acute traumatic spinal cord injury: a systematic review of the literature

JC Furlan, V Noonan, A Singh… - Journal of …, 2011 - liebertpub.com
The most common primary end-point of the trial on treatment of traumatic spinal cord injury
(SCI) is the degree of impairment. The American Spinal Injury Association (ASIA) Standards …

International standards for neurological classification of spinal cord injury: impact of the revised worksheet (revision 02/13) on classification performance

C Schuld, S Franz, K Brüggemann… - The journal of spinal …, 2016 - Taylor & Francis
Study Design: Prospective cohort study. Objectives: Comparison of the classification
performance between the worksheet revisions of 2011 and 2013 of the International …