A critical review on the potential impacts of neonicotinoid insecticide use: current knowledge of environmental fate, toxicity, and implications for human health

DA Thompson, HJ Lehmler, DW Kolpin… - … Science: Processes & …, 2020 - pubs.rsc.org
Neonicotinoid insecticides are widely used in both urban and agricultural settings around
the world. Historically, neonicotinoid insecticides have been viewed as ideal replacements …

Insecticide resistance and its management in Bemisia tabaci species

AR Horowitz, M Ghanim, E Roditakis, R Nauen… - Journal of Pest …, 2020 - Springer
The sweet potato (cotton) whitefly Bemisia tabaci is a major agricultural pest in various fields
and vegetable crops worldwide. It causes extensive damage by direct feeding on plants …

The global status of insect resistance to neonicotinoid insecticides

C Bass, I Denholm, MS Williamson, R Nauen - Pesticide biochemistry and …, 2015 - Elsevier
The first neonicotinoid insecticide, imidacloprid, was launched in 1991. Today this class of
insecticides comprises at least seven major compounds with a market share of more than …

Neonicotinoid insecticides: molecular targets, resistance, and toxicity

K Matsuda, M Ihara, DB Sattelle - Annual review of …, 2020 - annualreviews.org
Neonicotinoids have been used to protect crops and animals from insect pests since the
1990s, but there are concerns regarding their adverse effects on nontarget organisms …

Do novel insecticides pose a threat to beneficial insects?

H Siviter, F Muth - Proceedings of the Royal Society B, 2020 - royalsocietypublishing.org
Systemic insecticides, such as neonicotinoids, are a major contributor towards beneficial
insect declines. This has led to bans and restrictions on neonicotinoid use globally, most …

Structure simplification of natural products as a lead generation approach in agrochemical discovery

TC Sparks, SO Duke - Journal of Agricultural and Food Chemistry, 2021 - ACS Publications
Natural products (NPs) have a long history as sources of compounds for crop protection.
Perhaps a more important role for NPs has been as models and inspiration for the discovery …

Applications of bioisosteres in the design of biologically active compounds

NA Meanwell - Journal of Agricultural and Food Chemistry, 2023 - ACS Publications
The design of bioisosteres represents a creative and productive approach to improve a
molecule, including by enhancing potency, addressing pharmacokinetic challenges …

Neonicotinoids and other insect nicotinic receptor competitive modulators: progress and prospects

JE Casida - Annual Review of Entomology, 2018 - annualreviews.org
Neonicotinoids (neonics) are remarkably effective as plant systemics to control sucking
insects and for flea control on dogs and cats. The nitroimines imidacloprid, clothianidin …

Lethal and sublethal synergistic effects of a new systemic pesticide, flupyradifurone (Sivanto®), on honeybees

S Tosi, JC Nieh - Proceedings of the Royal Society B, 2019 - royalsocietypublishing.org
The honeybee (Apis mellifera L.) is an important pollinator and a model for pesticide effects
on insect pollinators. The effects of agricultural pesticides on honeybee health have …

Fluorine-containing agrochemicals in the last decade and approaches for fluorine incorporation

Q Wang, H Song, Q Wang - Chinese Chemical Letters, 2022 - Elsevier
In this review, the methodologies for fluorine incorporation of 40 fluorine-containing
agrochemicals that received an international standardization organization (ISO) name …