Research on psoriasis pathogenesis has largely increased knowledge on skin biology in
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …

Over the past three decades, a considerable body of evidence has highlighted T cells as
pivotal culprits in the pathogenesis of psoriasis. This includes the association of psoriasis …

Infectious diseases have a profound impact on our health and many studies suggest that
host genetics play a major role in the pathogenesis of most of them. We perform 23 genome …

Psoriasis is a prevalent, chronic inflammatory disease of the skin, mediated by crosstalk
between epidermal keratinocytes, dermal vascular cells, and immunocytes such as antigen …

Research into the pathophysiology of psoriasis has shed light onto many fascinating
immunological interactions and underlying genetic constellations. Most prominent among …

IL-17A is pivotal in the etiology of psoriasis, and CD8+ T cells with the ability to produce this
cytokine (Tc17 cells) are over-represented in psoriatic lesions. Here we demonstrate that the …

This paper reviews current indications for otolaryngology consultation for tonsillectomy and
adenoidectomy (T&A). Despite often being performed concurrently, these procedures should …

Psoriasis is a chronic, immune-mediated disorder with cutaneous and systemic
manifestations. Genetic predisposition, environmental factors, and immune dysfunction all …

Introduction:'Chronic inflammatory immune-related skin disease'(ISDs) is an umbrella term
grouping together heterogeneous entities characterized by chronic inflammation potentially …

Psoriasis encompasses a group of related immune‐mediated inflammatory skin diseases
that affect up to 3% of the population. These diseases are heritable and over 40 genetic …