Psoriasis pathogenesis and treatment
A Rendon, K Schäkel - International journal of molecular sciences, 2019 - mdpi.com
Research on psoriasis pathogenesis has largely increased knowledge on skin biology in
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …
Adaptive and innate immunity in psoriasis and other inflammatory disorders
MP Schön - Frontiers in immunology, 2019 - frontiersin.org
Over the past three decades, a considerable body of evidence has highlighted T cells as
pivotal culprits in the pathogenesis of psoriasis. This includes the association of psoriasis …
pivotal culprits in the pathogenesis of psoriasis. This includes the association of psoriasis …
Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections
C Tian, BS Hromatka, AK Kiefer, N Eriksson… - Nature …, 2017 - nature.com
Infectious diseases have a profound impact on our health and many studies suggest that
host genetics play a major role in the pathogenesis of most of them. We perform 23 genome …
host genetics play a major role in the pathogenesis of most of them. We perform 23 genome …
Current knowledge on psoriasis and autoimmune diseases
N Ayala-Fontánez, DC Soler… - Psoriasis: Targets and …, 2016 - Taylor & Francis
Psoriasis is a prevalent, chronic inflammatory disease of the skin, mediated by crosstalk
between epidermal keratinocytes, dermal vascular cells, and immunocytes such as antigen …
between epidermal keratinocytes, dermal vascular cells, and immunocytes such as antigen …
The interleukin-23/interleukin-17 axis links adaptive and innate immunity in psoriasis
MP Schön, L Erpenbeck - Frontiers in immunology, 2018 - frontiersin.org
Research into the pathophysiology of psoriasis has shed light onto many fascinating
immunological interactions and underlying genetic constellations. Most prominent among …
immunological interactions and underlying genetic constellations. Most prominent among …
[HTML][HTML] The IL-17A-producing CD8+ T-cell population in psoriatic lesional skin comprises mucosa-associated invariant T cells and conventional T cells
MBM Teunissen, NG Yeremenko, DLP Baeten… - Journal of Investigative …, 2014 - Elsevier
IL-17A is pivotal in the etiology of psoriasis, and CD8+ T cells with the ability to produce this
cytokine (Tc17 cells) are over-represented in psoriatic lesions. Here we demonstrate that the …
cytokine (Tc17 cells) are over-represented in psoriatic lesions. Here we demonstrate that the …
Current indications for tonsillectomy and adenoidectomy
DA Randall - The Journal of the American Board of Family …, 2020 - Am Board Family Med
This paper reviews current indications for otolaryngology consultation for tonsillectomy and
adenoidectomy (T&A). Despite often being performed concurrently, these procedures should …
adenoidectomy (T&A). Despite often being performed concurrently, these procedures should …
Roles of infection in psoriasis
S Zhou, Z Yao - International journal of molecular sciences, 2022 - mdpi.com
Psoriasis is a chronic, immune-mediated disorder with cutaneous and systemic
manifestations. Genetic predisposition, environmental factors, and immune dysfunction all …
manifestations. Genetic predisposition, environmental factors, and immune dysfunction all …
Epidemiology of major chronic inflammatory immune-related skin diseases in 2019
Introduction:'Chronic inflammatory immune-related skin disease'(ISDs) is an umbrella term
grouping together heterogeneous entities characterized by chronic inflammation potentially …
grouping together heterogeneous entities characterized by chronic inflammation potentially …
Psoriasis and related disorders
AD Burden, B Kirby - Rook's Textbook of Dermatology, Ninth …, 2016 - Wiley Online Library
Psoriasis encompasses a group of related immune‐mediated inflammatory skin diseases
that affect up to 3% of the population. These diseases are heritable and over 40 genetic …
that affect up to 3% of the population. These diseases are heritable and over 40 genetic …