CCAAT/enhancer-binding proteins: structure, function and regulation
CCAAT/enhancer binding proteins (C/EBPs) are a family of transcription factors that all
contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in …
contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in …
Liver-enriched transcription factors in liver function and development. Part II: the C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian …
H Schrem, J Klempnauer, J Borlak - Pharmacological reviews, 2004 - ASPET
In the first part of our review (see Pharmacol Rev 2002; 54: 129-158), we discussed the
basic principles of gene transcription and the complex interactions within the network of …
basic principles of gene transcription and the complex interactions within the network of …
IL-6 upregulates a disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS-2) in human osteosarcoma cells mediated by JNK pathway
Abstract ADAMTS-2 and ADAMTS-3 (a disintegrin and metalloproteinase with
thrombospondin type 1 motif 2) belong to the procollagen aminoproteinase subfamily of …
thrombospondin type 1 motif 2) belong to the procollagen aminoproteinase subfamily of …
xDnmt1 regulates transcriptional silencing in pre-MBT Xenopusembryos independently of its catalytic function
DS Dunican, A Ruzov, JA Hackett, RR Meehan - 2008 - journals.biologists.com
We previously reported that the maintenance cytosine methyltransferase xDnmt1 is essential
for gene silencing in early Xenopus laevis embryos. In the present study, we show that …
for gene silencing in early Xenopus laevis embryos. In the present study, we show that …
Interferon-γ stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2: A Potentially novel pathway for …
JR Mead, TR Hughes, SA Irvine, NN Singh… - Journal of Biological …, 2003 - ASBMB
Interferon-γ (IFN-γ) is a pleiotropic cytokine that modulates the immune function, cell
proliferation, apoptosis, macrophage activation, and numerous other cellular responses …
proliferation, apoptosis, macrophage activation, and numerous other cellular responses …
SP1 and USF differentially regulate ADAMTS1 gene expression under normoxic and hypoxic conditions in hepatoma cells
SA Turkoglu, F Kockar - Gene, 2016 - Elsevier
ADAM metallopeptidase with thrombospondin type I motif, 1 (ADAMTS1) that has both
antiangiogenic and aggrecanase activity was dysregulated in many pathophysiologic …
antiangiogenic and aggrecanase activity was dysregulated in many pathophysiologic …
A critical role for the Sp1-binding sites in the transforming growth factor-β-mediated inhibition of lipoprotein lipase gene expression in macrophages
Increasing evidence suggests that the cytokine transforming growth factor-β (TGF-β) inhibits
the development of atherosclerosis. The lipoprotein lipase (LPL) enzyme expressed by …
the development of atherosclerosis. The lipoprotein lipase (LPL) enzyme expressed by …
A novel role of Sp1 and Sp3 in the interferon-γ-mediated suppression of macrophage lipoprotein lipase gene transcription
TR Hughes, TS Tengku-Muhammad, SA Irvine… - Journal of Biological …, 2002 - ASBMB
The regulation of macrophage lipoprotein lipase by cytokines is of potentially crucial
importance in the pathogenesis of atherosclerosis. We have shown previously that …
importance in the pathogenesis of atherosclerosis. We have shown previously that …
SP1-mediated downregulation of ADAMTS3 gene expression in osteosarcoma models
ADAMTS3 is a member of procollagen N-proteinase subfamily of ADAMTS (a disintegrin
and metalloproteinase with thrombospondin motifs) gene family. It has an important function …
and metalloproteinase with thrombospondin motifs) gene family. It has an important function …
Functional analysis of the chicken PPARγ gene 5′-flanking region and C/EBPα-mediated gene regulation
N Ding, Y Gao, N Wang, H Li - … and Physiology Part B: Biochemistry and …, 2011 - Elsevier
Peroxisome proliferator-activated receptor-γ (PPARγ) and CCAAT/enhancer binding protein-
α (C/EBPα) are the master regulators of adipogenesis. The regulatory mechanism of PPARγ …
α (C/EBPα) are the master regulators of adipogenesis. The regulatory mechanism of PPARγ …