Acute traumatic spinal cord injury

I Eli, DP Lerner, Z Ghogawala - Neurologic clinics, 2021 - neurologic.theclinics.com
Acute traumatic spinal cord injury (SCI) is typically associated with devastating outcomes.
The injury to the spinal cord results in damage to motor, sensory, and autonomic functions of …

Traumatic spinal cord injury

CS Ahuja, JR Wilson, S Nori, M Kotter… - Nature reviews Disease …, 2017 - nature.com
Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social and
vocational well-being of patients. The demographic of SCIs is shifting such that an …

From basics to clinical: a comprehensive review on spinal cord injury

NA Silva, N Sousa, RL Reis, AJ Salgado - Progress in neurobiology, 2014 - Elsevier
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Pathophysiology and therapeutic approaches for spinal cord injury

R Lima, A Monteiro, AJ Salgado, S Monteiro… - International Journal of …, 2022 - mdpi.com
Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …

Regenerative therapies for central nervous system diseases: a biomaterials approach

RY Tam, T Fuehrmann, N Mitrousis… - …, 2014 - nature.com
The central nervous system (CNS) has a limited capacity to spontaneously regenerate
following traumatic injury or disease, requiring innovative strategies to promote tissue and …

Mean arterial blood pressure correlates with neurological recovery after human spinal cord injury: analysis of high frequency physiologic data

G Hawryluk, W Whetstone, R Saigal… - Journal of …, 2015 - liebertpub.com
Current guidelines for the care of patients with acute spinal cord injuries (SCIs) recommend
maintaining mean arterial pressure (MAP) values of 85–90 mm Hg for 7 days after an acute …

Anxiety and depression in patients with traumatic spinal cord injury: a nationwide population-based cohort study

SW Lim, YL Shiue, CH Ho, SC Yu, PH Kao, JJ Wang… - PloS one, 2017 - journals.plos.org
Background Traumatic spinal cord injury (tSCI) may involve new-onset anxiety and
depression post-discharge. However, long-term population-based studies have lacked …

Intervertebral disk degeneration in dogs: consequences, diagnosis, treatment, and future directions

ND Jeffery, JM Levine, NJ Olby… - Journal of veterinary …, 2013 - Wiley Online Library
Evidence of intervertebral disk degeneration (IVDD) is extremely common in dogs, and its
prevalence increases with age. It has many important consequences because degeneration …

Timing of decompression in patients with acute spinal cord injury: a systematic review

JR Wilson, LA Tetreault, BK Kwon… - Global spine …, 2017 - journals.sagepub.com
Study Design: Systematic review. Objective: To conduct a systematic review and synthesis of
the literature to assess the comparative effectiveness, safety, and cost-effectiveness of early …

A new three dimensional biomimetic hydrogel to deliver factors secreted by human mesenchymal stem cells in spinal cord injury

I Caron, F Rossi, S Papa, R Aloe, M Sculco, E Mauri… - Biomaterials, 2016 - Elsevier
Stem cell therapy with human mesenchymal stem cells (hMSCs) represents a promising
strategy in spinal cord injury (SCI). However, both systemic and parenchymal hMSCs …