CD117 (KIT) is a type III receptor tyrosine kinase operating in cell signal transduction in
several cell types. Normally KIT is activated (phosphorylated) by binding of its ligand, the …

Context—Histologic diagnosis of renal neoplasm is usually straightforward by routine light
microscopy. However, immunomarkers may be essential in several contexts, including …

Cell-lineage-specific transcription factors are a group of regulatory proteins expressed in
embryonic, differentiated, or neoplastic cells of the same lineage and represent a valuable …

Context Eosinophilic renal neoplasms include a spectrum of solid and papillary tumors
ranging from indolent benign oncocytoma to highly aggressive malignancies. Recognition of …

Context.—The separation of chromophobe renal cell carcinoma, oncocytoma, and clear cell
renal cell carcinoma using light microscopy remains problematic in some cases. Objective …

CONTEXT: Renal cell carcinoma (RCC) in adults comprises a heterogeneous group of
tumours with variable clinical outcomes that range from indolent to overtly malignant. The …

Renal cell carcinomas (RCCs) of different histologic subtypes differ in their prognosis and
therapeutic response; therefore, it is important to classify malignant epithelial tumors of the …

Renal cell carcinomas (RCCs) harboring the t (6; 11)(p21; q12) translocation were first
described in 2001 and recently recognized by the 2013 International Society of Urological …

We report a series of 10 oncocytic renal papillary tumors, with the aim of determining their
clinicopathologic features. All patients were male (median age, 71 years), treated by radical …

Molecular and morphologic interrogation has driven a much-needed reexamination of renal
cell carcinoma (RCC). Indeed, the recently released 2016 World Health Organization …