Animal models of drug relapse and craving after voluntary abstinence: a review
Relapse to drug use during abstinence is a defining feature of addiction. During the last
several decades, this clinical scenario has been studied at the preclinical level using classic …
several decades, this clinical scenario has been studied at the preclinical level using classic …
Stress-induced reinstatement of drug seeking: 20 years of progress
In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this
clinical scenario has been studied using a rat model of stress-induced reinstatement of drug …
clinical scenario has been studied using a rat model of stress-induced reinstatement of drug …
Understanding addiction using animal models
Drug addiction is a neuropsychiatric disorder with grave personal consequences that has an
extraordinary global economic impact. Despite decades of research, the options available to …
extraordinary global economic impact. Despite decades of research, the options available to …
The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research
Background and rationale Results from many clinical studies suggest that drug relapse and
craving are often provoked by acute exposure to the self-administered drug or related drugs …
craving are often provoked by acute exposure to the self-administered drug or related drugs …
Opiate versus psychostimulant addiction: the differences do matter
The publication of the psychomotor stimulant theory of addiction in 1987 and the finding that
addictive drugs increase dopamine concentrations in the rat mesolimbic system in 1988 …
addictive drugs increase dopamine concentrations in the rat mesolimbic system in 1988 …
The lateral habenula in addiction and depression: an anatomical, synaptic and behavioral overview
The lateral habenula (LH b) is an epithalamic region with a crucial role in the regulation of
midbrain monoaminergic systems. Over the past few years a renewed interest in the LH b …
midbrain monoaminergic systems. Over the past few years a renewed interest in the LH b …
Incubation of methamphetamine but not heroin craving after voluntary abstinence in male and female rats
We recently introduced an animal model of incubation of methamphetamine craving after
choice-based voluntary abstinence in male rats. Here we studied the generality of this …
choice-based voluntary abstinence in male rats. Here we studied the generality of this …
Effect of the novel positive allosteric modulator of metabotropic glutamate receptor 2 AZD8529 on incubation of methamphetamine craving after prolonged voluntary …
Background Cue-induced methamphetamine craving increases after prolonged forced
(experimenter-imposed) abstinence from the drug (incubation of methamphetamine …
(experimenter-imposed) abstinence from the drug (incubation of methamphetamine …
The central amygdala nucleus is critical for incubation of methamphetamine craving
X Li, T Zeric, S Kambhampati, JM Bossert… - …, 2015 - nature.com
Cue-induced methamphetamine seeking progressively increases after withdrawal but
mechanisms underlying this 'incubation of methamphetamine craving'are unknown. Here we …
mechanisms underlying this 'incubation of methamphetamine craving'are unknown. Here we …
Roux-en-Y gastric bypass surgery changes food reward in rats
Objective: To examine hedonic reactions to palatable foods and food choice behavior in an
established rat model of RYGB. Methods and Design: Male Sprague–Dawley (SD) rats and …
established rat model of RYGB. Methods and Design: Male Sprague–Dawley (SD) rats and …