Background: The connection between uric acid (UA) and renal impairment is well known
due to the urate capacity to precipitate within the tubules or extra-renal system. Emerging …

Generating reactive oxygen species (ROS) is necessary for both physiology and pathology.
An imbalance between endogenous oxidants and antioxidants causes oxidative stress …

Cellular senescence is an irreversible state of cell cycle arrest occurring in response to
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …

Uric acid is the end product of purine metabolism in humans, and its excessive accumulation
leads to hyperuricemia and urate crystal deposition in tissues including joints and kidneys …

Caffeine is the most frequently used substance with a central nervous system stimulant
effect, but its consumption is most often due to the intake of foods and drinks that contain it …

Hyperuricemia is a disease caused by an increase in uric acid levels in the blood. Currently,
various treatments are developed by utilizing natural ingredients as an anti-hyperuricemia …

Cardiovascular diseases (CVDs), especially those involving a systemic inflammatory
process such as atherosclerosis, remain the leading cause of morbidity and mortality in …

Recent evidence suggests that probiotics, prebiotics and synbiotics may serve as important
dietary components in the prevention (especially) and treatment of cardiovascular diseases …

Diabetic nephropathy (DN) is a common pathological feature in patients with diabetes and
the leading cause of end-stage renal disease. Although several pharmacological agents …

Objectives: There is growing evidence that antioxidant-rich diets protect against chronic
kidney disease (CKD). However, the relationship between the Composite Dietary …