[HTML][HTML] Ketamine for pain
K Jonkman, A Dahan, T van de Donk, L Aarts… - …, 2017 - ncbi.nlm.nih.gov
The efficacy of the N-methyl-D-aspartate receptor antagonist ketamine as an analgesic
agent is still under debate, especially for indications such as chronic pain. To understand the …
agent is still under debate, especially for indications such as chronic pain. To understand the …
Pharmacokinetic and pharmacodynamic considerations for NMDA-receptor antagonist ketamine in the treatment of chronic neuropathic pain: an update of the most …
J Kamp, M Van Velzen, E Olofsen, M Boon… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Chronic neuropathic pain (NP) is an incapacitating illness caused by a lesion of
the somatosensory nervous system and is associated with several diseases or syndromes …
the somatosensory nervous system and is associated with several diseases or syndromes …
[HTML][HTML] Obesity by high-fat diet increases pain sensitivity by reprogramming branched-chain amino acid catabolism in dorsal root ganglia
N Lian, K Luo, H Xie, Y Kang, K Tang, P Lu… - Frontiers in Nutrition, 2022 - frontiersin.org
Obesity is a significant health concern as a result of poor-quality diet, for example, high-fat
diet (HFD). Although multiple biological and molecular changes have been identified to …
diet (HFD). Although multiple biological and molecular changes have been identified to …
[HTML][HTML] Obesity and incident prescription opioid use in the US, 2000–2015
Introduction Prior studies have identified associations between obesity and numerous
conditions that increase risks for chronic pain. However, the impact of obesity on prescription …
conditions that increase risks for chronic pain. However, the impact of obesity on prescription …
[HTML][HTML] The effect of body mass index on thoracic paravertebral block analgesia after video-assisted thoracoscopic surgery; a prospective interventional study
EN Zengin, A Alagöz, H Yiğit, H Sazak, S Şekerci… - BMC …, 2023 - Springer
Background To investigate the effects of body mass index (BMI) on intensity postoperative
pain in patients who underwent thoracic paravertebral block (TPVB) for postoperative …
pain in patients who underwent thoracic paravertebral block (TPVB) for postoperative …
Neuroendocrine and neuroimmune mechanisms underlying comorbidity of pain and obesity
DH Zhang, YH Fan, YQ Zhang, H Cao - Life Sciences, 2023 - Elsevier
Pain and obesity, as well as their associated impairments, are major health concerns.
Understanding the relationship between the two is the focus of a growing body of research …
Understanding the relationship between the two is the focus of a growing body of research …
Respiratory Effects of Biased Ligand Oliceridine in Older Volunteers: A Pharmacokinetic–Pharmacodynamic Comparison with Morphine
P Simons, R van der Schrier, M van Lemmen… - …, 2023 - pubs.asahq.org
Background Oliceridine is a G protein–biased µ-opioid, a drug class that is associated with
less respiratory depression than nonbiased opioids, such as morphine. The authors …
less respiratory depression than nonbiased opioids, such as morphine. The authors …
[HTML][HTML] Deleterious effects of higher body mass index on subjective and objective measures of chemotherapy-induced peripheral neuropathy in cancer survivors
I Petrovchich, KM Kober, L Wagner, SM Paul… - Journal of pain and …, 2019 - Elsevier
Context Recent, albeit, limited evidence suggests that body mass index (BMI) may be a
modifiable risk factor to reduce the deleterious effects of chemotherapy-induced peripheral …
modifiable risk factor to reduce the deleterious effects of chemotherapy-induced peripheral …
[HTML][HTML] Opioid Analgesics after Bariatric Surgery: A Scoping Review to Evaluate Physiological Risk Factors for Opioid-Related Harm
SCM Wuyts, B Torensma, AFA Schellekens… - Journal of clinical …, 2023 - mdpi.com
The persisting use of opioids following bariatric surgery has emerged as a prevalent
complication, heightening the probability of opioid-related harm (ORM), such as opioid …
complication, heightening the probability of opioid-related harm (ORM), such as opioid …
[HTML][HTML] Pain sensitivity does not differ between obese and healthy weight individuals
NM Emerson, H Nahman-Averbuch, JL Peugh… - Pain …, 2021 - journals.lww.com
Objectives: The aim of this study was to determine whether pain-free obese individuals
display altered pain responses to acute noxious stimuli, thus raising the possibility of greater …
display altered pain responses to acute noxious stimuli, thus raising the possibility of greater …