Peripheral nerve injury (PNI) caused by trauma, chronic disease and other factors may lead
to partial or complete loss of sensory, motor and autonomic functions, as well as neuropathic …

Autograft replaced by a nerve guidance conduit (NGC) is challenging in peripheral nerve
injury because current NGC is still limited by precise conductivity and excellent …

The understanding of nanomaterial biology determines material selection and scaffold
fabrication in regenerative medicine. The translational application of advanced functional …

Injuries to the peripheral nervous system are a common clinical issue, causing dysfunctions
of the motor and sensory systems. Surgical interventions such as nerve autografting are …

The pursuit of effective therapeutic strategies for tissue damage has prompted extensive
scholarly investigations worldwide. Tissue engineering has emerged as a prominent …

Appropriate animal models, mimicking conditions of both health and disease, are needed to
understand not only the biology and the physiology of neurons and other cells under normal …

Dextro-chirality is reported to specifically promote the proliferation and survival of neural
cells. However, applying this unique performance to nerve repair remains a great challenge …

Biomaterials can modulate the local immune microenvironments to promote peripheral
nerve regeneration. Inspired by the spatial orderly distribution and endogenous electric field …

Background Chronic ankle instability (CAI) is a common sequela following an acute lateral
ankle sprain (LAS). To treat an acute LAS more effectively and efficiently, it is important to …

The effective treatment of long-gap peripheral nerve injury (PNI) remains a challenge in
clinical settings. The autograft, the gold standard for the long-gap PNI therapy, has several …