Oxidative stress (OS), defined as an overabundance of reactive oxygen species (ROS) or a
deficiency of antioxidants, has been linked to sperm damage and male infertility. There are …

Objective To examine the potential effects of lifestyle factors on male reproductive health.
Evidence of a global decline in human sperm quality over recent decades has been …

BACKGROUND Infertility is a global public health issue, affecting 15% of all couples of
reproductive age. Male factors, including decreased semen quality, are responsible for …

Aging men display reduced reproductive health; however, testis aging is poorly understood
at the molecular and genomic levels. Here, we utilized single-cell RNA-seq to profile over …

Defective sperm function has been identified as the most common cause of infertility. The
objective of this study was to review recent findings on the effects of various antioxidants on …

The present updated systematic review and meta‐analysis aims to summarize the evidence
from published studies with low risk for any important bias (based on methodological quality …

In recent decades, the worldwide prevalence of obesity has risen dramatically and is
currently estimated to be around 20%. Obesity is linked to an increased risk of comorbidities …

Recent evidence has shown that the sperm epigenome is vulnerable to dynamic
modifications arising from a variety of paternal environment exposures and that this legacy …

Alongside an increasing prevalence of couple and male infertility, evidence suggests there
is a global declining trend in male fertility parameters over the past few decades. This may …

Results Among the myriad of publications reviewed in this paper, impaired spermatogenesis
and sexual dysfunction have been shown to drive other variables towards poor fertility …