Gut microbiota in colorectal cancer development and therapy

CC Wong, J Yu - Nature Reviews Clinical Oncology, 2023 - nature.com
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

[HTML][HTML] Characterization of the internal working-life exposome using minimally and non-invasive sampling methods-a narrative review

E Verscheure, R Stierum, V Schlünssen… - Environmental …, 2023 - Elsevier
During recent years, we are moving away from the 'one exposure, one disease'-approach in
occupational settings and towards a more comprehensive approach, taking into account the …

Promising epigenetic biomarkers for the early detection of colorectal cancer: a systematic review

SA Anghel, CB Ioniță-Mîndrican, I Luca, AL Pop - Cancers, 2021 - mdpi.com
Simple Summary High-performance, non-invasive screening is a requirement in colorectal
cancer (CRC) as early detection is a key in reducing disease-related mortality in CRC …

[HTML][HTML] A systematic review of microbiome-derived biomarkers for early colorectal cancer detection

FH Zwezerijnen-Jiwa, H Sivov, P Paizs… - Neoplasia, 2023 - Elsevier
Increasing evidence suggests a role of the gut microbiome in the development of colorectal
cancer (CRC) and that it can serve as a biomarker for early diagnosis. This review aims to …

Feasibility of quantification based on novel evaluation with stool DNA and fecal immunochemical test for colorectal cancer detection

H Xu, H Chen, J Hu, Z Xiong, D Li, S Wang, J Yu - BMC gastroenterology, 2022 - Springer
Abstract Background Stool DNA (sDNA) tests and fecal immunochemical test (FIT) are used
for the detection of colorectal cancer (CRC). Here we performed a novel evaluation using …

Comprehensive microRNA analysis across genome-edited colorectal cancer organoid models reveals miR-24 as a candidate regulator of cell survival

JW Villanueva, L Kwong, T Han, SA Martinez… - Bmc Genomics, 2022 - Springer
Somatic mutations drive colorectal cancer (CRC) by disrupting gene regulatory
mechanisms. Distinct combinations of mutations can result in unique changes to regulatory …

Future of colorectal cancer screening: from one-size-fits-all to tailor-made

T Kortlever, M van der Vlugt, E Dekker - Frontiers in Gastroenterology, 2022 - frontiersin.org
Screening for colorectal cancer (CRC) and its precursor lesions, advanced adenomas (AA),
has been shown to effectively reduce CRC-related mortality. However, the method of CRC …

A novel stool methylation test for the non-invasive screening of gastric and colorectal cancer

L Ma, J Gong, M Zhao, X Kong, P Gao, Y Jiang… - Frontiers in …, 2022 - frontiersin.org
Background Because of poor compliance or low sensitivity, existing diagnostic approaches
are unable to provide an efficient diagnosis of patients with gastric and colorectal cancer …

[HTML][HTML] INVITED REVIEW: Camel Milk and Gut Health: Understanding Digestibility and the Impact on Gut Microbiota

AH Ali, S Li, SQ Liu, RY Gan, HB Li, A Kamal-Eldin… - Journal of Dairy …, 2023 - Elsevier
Camel milk (CM), known for its immune-regulatory, anti-inflammatory, antiapoptotic, and
antidiabetic properties, is a natural healthy food. It is easily digestible due to the high levels …

Evaluation of combined detection of multigene mutation and SDC2/SFRP2 methylation in stool specimens for colorectal cancer early diagnosis

J Lin, L Zhang, M Chen, J Chen, Y Wu, T Wang… - International Journal of …, 2022 - Springer
Purpose Molecular diagnostics of colorectal cancer (CRC) can be used as an auxiliary
approach for patients recommended for colonoscopy, providing more CRC supplemental …