Clinical predictors of neurological outcome, functional status, and survival after traumatic spinal cord injury: a systematic review

JR Wilson, DW Cadotte, MG Fehlings - Journal of neurosurgery: spine, 2012 - thejns.org
Object The object of this study was to identify, by means of a systematic review of the
literature, the acute clinical predictors of neurological outcome, functional outcome, and …

Review of transplantation of neural stem/progenitor cells for spinal cord injury

AJ Mothe, CH Tator - International Journal of Developmental Neuroscience, 2013 - Elsevier
Spinal cord injury (SCI) is a debilitating condition often resulting in paralysis, yet currently
there is no effective treatment. Stem cell transplantation is a promising therapeutic strategy …

A clinical prediction rule for ambulation outcomes after traumatic spinal cord injury: a longitudinal cohort study

JJ van Middendorp, AJF Hosman, ART Donders… - The Lancet, 2011 - thelancet.com
Background Traumatic spinal cord injury is a serious disorder in which early prediction of
ambulation is important to counsel patients and to plan rehabilitation. We developed a …

A clinical prediction model for long-term functional outcome after traumatic spinal cord injury based on acute clinical and imaging factors

JR Wilson, RG Grossman, RF Frankowski… - Journal of …, 2012 - liebertpub.com
To improve clinicians' ability to predict outcome after spinal cord injury (SCI) and to help
classify patients within clinical trials, we have created a novel prediction model relating …

Tackling the glial scar in spinal cord regeneration: new discoveries and future directions

A Shafqat, I Albalkhi, HM Magableh, T Saleh… - Frontiers in cellular …, 2023 - frontiersin.org
Axonal regeneration and functional recovery are poor after spinal cord injury (SCI), typified
by the formation of an injury scar. While this scar was traditionally believed to be primarily …

Recovery after spinal cord infarcts: long-term outcome in 115 patients

CE Robertson, RD Brown Jr, EFM Wijdicks… - Neurology, 2012 - AAN Enterprises
Objective: To investigate the long-term outcome of patients with spinal cord infarct (SCI) and
identify prognostic predictors. Methods: We reviewed 115 patients with SCI treated between …

Spinal cord trauma and the molecular point of no return

PK Yip, A Malaspina - Molecular neurodegeneration, 2012 - Springer
A mechanical trauma to the spinal cord can be followed by the development of irreversible
and progressive neurodegeneration, as opposed to a temporary or partially reversible …

Age decreases macrophage IL-10 expression: implications for functional recovery and tissue repair in spinal cord injury

B Zhang, WM Bailey, KJ Braun, JC Gensel - Experimental neurology, 2015 - Elsevier
Macrophages with different activation states are present after spinal cord injury (SCI). M1
macrophages purportedly promote secondary injury processes while M2 cells support axon …

Early surgical decompression improves neurological outcome after complete traumatic cervical spinal cord injury: a meta-analysis

PV Ter Wengel, PC De Witt Hamer, JC Pauptit… - Journal of …, 2019 - liebertpub.com
In patients with traumatic spinal cord injury (tSCI) a distinction in surgical urgency is made
on the basis of the severity of the initial neurological injury. The optimal timing of surgical …

Aging and miR-155 in mice influence survival and neuropathic pain after spinal cord injury

AD Gaudet, LK Fonken, MT Ayala, SF Maier… - Brain, behavior, and …, 2021 - Elsevier
Spinal cord injury (SCI) elicits chronic pain in 65% of individuals. In addition, SCI afflicts an
increasing number of aged individuals, and those with SCI are predisposed to shorter …