Zika virus (ZIKV) is an emerging virus from the Flaviviridae family that is transmitted to
humans by mosquito vectors and represents an important health problem. Infections in …

Viral encephalitis is a devastating disease with high mortality, and survivors often suffer from
severe neurological complications. Microglia are innate immune cells of the central nervous …

Since the discovery of the nuclear factor kappa B (NF-ĸB) transcription factor 36 years ago,
many studies have linked the NF-ĸB signaling pathway to pathological and physiological …

Zika virus (ZIKV) infection can be associated with neurological pathologies, such as
microcephaly in newborns and Guillain-Barre syndrome in adults. Effective therapeutics are …

Pellino1 (Peli1) is a highly conserved E3 Ub ligase that exerts its biological functions by
mediating target protein ubiquitination. Extensive evidence has demonstrated the crucial …

The Pellino family is a novel and well-conserved E3 ubiquitin ligase family and consists of
Pellino1, Pellino2, and Pellino3. Each family member exhibits a highly conserved structure …

Background. Placenta previa is a pregnancy condition associated with the development of
complications related to placental insufficiency, including hypertension, preeclampsia and …

c-FLIP functions as a dual regulator of apoptosis and inflammation, yet its implications in
Zika virus (ZIKV) infection remain partially understood, especially in the context of ZIKV …

The incidence of colitis‐associated colorectal cancer (CAC) has increased due to a high‐
nutrient diet, increased environmental stimuli and inherited gene mutations. To adequately …

Asian lineage Zika virus (ZIKV) strains emerged globally, causing outbreaks linked with
critical clinical disease outcomes unless the virus is effectively restricted by host immunity …