Hand-foot-and-mouth disease (HFMD) is a viral illness commonly seen in young children
under 5 years of age, characterized by typical manifestations such as oral herpes and …

Objective: This study reports a systematic review of the epidemiology of HFMD in Asia. Data
Sources: PubMed, Web of Science and Google Scholar were searched up to December …

Hand, foot, and mouth disease (HFMD) is a contagious viral disease and mainly affects
infants and young children. The main manifestations are fever, vesicular rashes on hand …

ABSTRACT On December 3rd 2015, the China Food and Drug Administration (CFDA)
approved the first inactivated Enterovirus 71 (EV71) whole virus vaccine for preventing …

Coxsackievirus 16 (CA16) is one of the major pathogens associated with hand, foot, and
mouth disease (HFMD) in infants and young children. In recent years, CA16 and human …

A previously well infant aged 9 months presented with an acute, self-limiting illness
characterised by high fever and a papular eruption that started on the face. Although fever …

Background In early 2020, non-pharmaceutical interventions (NPIs) were implemented in
China to reduce and contain the coronavirus disease 2019 (COVID-19) transmission. These …

Enteroviruses (EVs) are the most common viral agents in humans. Although most infections
are mild or asymptomatic, there is a wide spectrum of clinical manifestations that may be …

Enterovirus 71 (EV71) is a global infectious disease that affects millions of people. The virus
is the main etiological agent for hand, foot, and mouth disease with outbreaks and …

Human coxsackievirus A6 (CVA6) is an enterically transmitted enterovirus. Until recently,
CVA6 infections were considered as being of minor clinical significance, and only rarely …