The role of adipose tissue in cardiovascular health and disease

EK Oikonomou, C Antoniades - Nature Reviews Cardiology, 2019 - nature.com
Accumulating knowledge on the biology and function of the adipose tissue has led to a
major shift in our understanding of its role in health and disease. The adipose tissue is now …

[HTML][HTML] Cellular senescence in cardiac diseases

I Shimizu, T Minamino - Journal of cardiology, 2019 - Elsevier
Replicative capacity of somatic cells is limited. It indicates that aging also develops at the
cellular level, and this is described as “cellular senescence”. Senescent cells become …

[HTML][HTML] The link between chronic stress and accelerated aging

YE Yegorov, AV Poznyak, NG Nikiforov, IA Sobenin… - Biomedicines, 2020 - mdpi.com
People exposed to chronic stress age rapidly. The telomeres in their cells of all types
shorten faster. Inflammation is another important feature of stress that, along with aging …

[HTML][HTML] Telomere length: a cardiovascular biomarker and a novel therapeutic target

M Sagris, P Theofilis, AS Antonopoulos… - International Journal of …, 2022 - mdpi.com
Coronary artery disease (CAD) is a multifactorial disease with a high prevalence, particularly
in developing countries. Currently, the investigation of telomeres as a potential tool for the …

[HTML][HTML] State-of-the-art review article. Atherosclerosis affecting fat: what can we learn by imaging perivascular adipose tissue?

C Antoniades, CP Kotanidis, DS Berman - Journal of cardiovascular …, 2019 - Elsevier
Perivascular adipose tissue (PVAT) surrounding the human coronary arteries, secretes a
wide range of adipocytokines affecting the biology of the adjacent vascular wall in a …

The role and mechanism of hyperoside against myocardial infarction in mice by regulating autophagy via NLRP1 inflammation pathway

Y Yang, J Li, T Rao, Z Fang, J Zhang - Journal of Ethnopharmacology, 2021 - Elsevier
Abstract Ethnopharmacological relevance The genus Hypericum are widely distributed in
China. Hypericum perforatum L.(genus Hypericum, family Hypericaceae) has a long history …

Imaging of the pericoronary adipose tissue (PCAT) using cardiac computed tomography: modern clinical implications

M Goeller, S Achenbach, H Duncker… - Journal of thoracic …, 2021 - journals.lww.com
Modern coronary computed tomography angiography (CTA) is the gold standard to visualize
the epicardial adipose tissue (EAT) and pericoronary adipose tissue (PCAT). The EAT is a …

[HTML][HTML] Progress in Understanding Oxidative Stress, Aging, and Aging-Related Diseases

J Yang, J Luo, X Tian, Y Zhao, Y Li, X Wu - Antioxidants, 2024 - mdpi.com
Under normal physiological conditions, reactive oxygen species (ROS) are produced
through redox reactions as byproducts of respiratory and metabolic activities. However, due …

Perivascular fat imaging by computed tomography (CT): a virtual guide

CP Kotanidis, C Antoniades - British Journal of Pharmacology, 2021 - Wiley Online Library
Imaging in medicine has been revolutionised by technological, computational and research
advances over the past decades. Computed tomography (CT), in particular, has seen rapid …

[HTML][HTML] 17-year follow-up of association between telomere length and all-cause mortality, cardiovascular mortality in individuals with metabolic syndrome: results from …

L Xiong, G Yang, T Guo, Z Zeng, T Liao, Y Li… - Diabetology & Metabolic …, 2023 - Springer
Background The relationship between leukocyte telomere length (LTL) and mortality risk in
individuals with metabolic syndrome (MetS) remains poorly understood. This study aimed to …